Results 81 to 90 of about 4,179 (208)

Ensuring enantiomeric consistency in FAPI radiopharmaceuticals: comparative analysis of (S)- and (S/R)-FAPI-46/-74 confirms pharmacological equivalence

EJNMMI Radiopharmacy and Chemistry
Background Enantiomeric composition may impact binding and potentially performance of a drug product but is not routinely tested and minimum acceptance criteria are not always established.
Magdalena Staniszewska, Ralph Hübner, Camilla Locatelli, Douglas Howard, Matilde Forni, Francis Man, Bent Wilhelm Schoultz, Syed Nuruddin, Ingrid Sofie Norberg-Schulz Hagen, Sherly Mosessian, Ken Herrmann, Valeska von Kiedrowski, Katharina Lückerath   +12 more
doaj   +1 more source

[68Ga]Ga-FAPI PET/CT in brain tumors: comparison with [18F]F-FDG PET/CT

Frontiers in Oncology
PurposeTo investigate the feasibility of [68Ga]Ga-FAPI PET/CT in brain tumor imaging and to compare it with [18F]F-FDG PET/CT.Methods25 patients with MRI-suspected brain tumors were included in the study.
Ya Liu, Ya Liu, Ya Liu, Haoyuan Ding, Haoyuan Ding, Haoyuan Ding, Jianpeng Cao, Guangfu Liu, Guangfu Liu, Guangfu Liu, Yue Chen, Yue Chen, Yue Chen, Zhanwen Huang, Zhanwen Huang, Zhanwen Huang   +15 more
doaj   +1 more source

Noninvasive Monitoring of Early Cardiac Fibrosis in Diabetic Mice by [⁶⁸Ga]Ga-DOTA-FAPI-04 PET/CT Imaging

Cardiac fibrosis represents one of the representative pathological characteristics in the diabetic heart. Active fibroblasts play an essential role in the progression of cardiac fibrosis.
Junbo Ge (385426), Dai Shi (5396630), Ai Wang (1392052), Dengfeng Cheng (561007), Yan Yan (208529), Kaibin Lin (9911049)   +5 more
core   +1 more source

Clinical significance of diffuse [18F] AlF-NOTA-FAPI-04 uptake in the thyroid on PET/CT imaging

EJNMMI Research
Background Many patients undergoing [18F] AlF-NOTA-FAPI-04 (18F-FAPI) PET/CT demonstrated diffuse thyroid uptake. These findings created challenges for accurate interpretation due to the limited understanding of physiological and non-oncologic causes of ...
Ying Kou, Wei Diao, Zhuzhong Cheng, Yutang Yao   +3 more
doaj   +1 more source

Prognostic impact of discordant lesions on [18F]FDG and [68Ga]Ga-FAPI-04 PET/CT compared to histological FAP expression in neuroendocrine neoplasms

Frontiers in Nuclear Medicine
ObjectiveOn dual-tracer positron emission tomography/computed tomography (PET/CT) with 2-deoxy-2-[¹⁸F]fluoro-D-glucose ([¹⁸F]FDG) and fibroblast activation protein inhibitor ([⁶⁸Ga]Ga-FAPI-04), discordant lesions (FDG+/FAPI-) in aggressive neuroendocrine
Tim Jedamzik, Aleksander Kosmala, Stefan Kircher, Marieke Heinrich, Wiebke Schlötelburg, Andreas K. Buck, Alexander Meining, Alexander Meining, Rudolf A. Werner, Rudolf A. Werner, Rudolf A. Werner, Alexander Weich, Alexander Weich, Kerstin Michalski   +13 more
doaj   +1 more source

The FAP+ CAF subset in bladder cancer: A key driver of cancer cell stemness and a promising target for FAPI therapy

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Meiqian Li, Shikun Wang, Hua Xiao, Rong Hu, Yueyun Xie   +4 more
wiley   +1 more source

Efeito disposição na tomada de decisões financeiras: as diferenças entre investidor individual e institucional [PDF]

, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.Um dos focos da área de finanças comportamentais é compreender a tendência de comportamentos dos agentes financeiros. Um viés comportamental identificado na década
Lopez, Fernanda Holdorf
core  

Pancreatic Cancer—Advances in the Last 50 Years

World Journal of Surgery, Volume 50, Issue 8, Page 2106-2115, August 2026.
S. George Barreto, Anirban Maitra, Eileen M. O'Reilly, Dushyant Sahani, Richard Zheng, Charles J. Yeo   +5 more
wiley   +1 more source

Impact of FAPI-46/dual-tracer PET/CT imaging on radiotherapeutic management in esophageal cancer

Radiation Oncology
Background Fibroblast activation protein (FAP) is expressed in the tumor microenvironment (TME) of various cancers. In our analysis, we describe the impact of dual-tracer imaging with Gallium-68-radiolabeled inhibitors of FAP (FAPI-46-PET/CT) and ...
Simone Wegen, Karina Claus, Philipp Linde, Johannes Rosenbrock, Maike Trommer, Thomas Zander, Armin Tuchscherer, Christiane Bruns, Hans Anton Schlößer, Wolfgang Schröder, Marie-Lisa Eich, Thomas Fischer, Klaus Schomäcker, Alexander Drzezga, Carsten Kobe, Katrin Sabine Roth, Jasmin Josefine Weindler   +16 more
doaj   +1 more source

Novel immunotheranostic FAP-inhibitor target modules for imaging and elimination of FAP-positive cells by UniCAR T-cells

OncoImmunology
The fibroblast activation protein alpha (FAPα) is overexpressed in the tumor microenvironment of most solid cancers and, in some cases, in cancer cells, making it an interesting target for theranostic applications.
Hugo Boutier, Jürgen Kogler, Liliana R. Loureiro, Christin Neuber, Nicole Berndt, Claudia Arndt, Sven Stadlbauer, Holger Stephan, Anja Feldmann, Klaus Kopka, Christoph E. Hagemeyer, Michael Bachmann   +11 more
doaj   +1 more source