Results 61 to 70 of about 4,179 (208)

Vooruitgang en toekomstperspectieven van beeldvorming met FAPI-PET/CT

, 2023
Het radiofarmacon 18F-fluorodeoxyglucose (FDG) is momenteel het werkpaard voor PET-diagnostiek. 18F-FDG is een universele tracer voor de diagnostiek van tumoren en infecties, met bijbehorende beperkingen ten aanzien van de specificiteit. De sensitiviteit
Bongers, V, Veldhuijzen van Zanten, Sophie, Jansen, S.M.A.   +2 more
core   +4 more sources

A AVALIAÇÃO DA DOR DO RECÉM-NASCIDO REALIZADA PELA EQUIPE DE ENFERMAGEM

UNINGÁ Review, 2018
Analisar e descrever a avaliação da dor do recém-nascido realizado pela equipe de enfermagem e ressaltaras principais dificuldades enfrentadas pelos enfermeiros.
LUANA MENDES SILVA, ANDRIENNY SANTANA DA SILVA, ÉRIKA WANESSA OLIVEIRA FURTADO ANDRADE, AMANDA PEREIRA DE AZEVEDO, FRANCISCA WINOLA SILVA DA COSTA, MARIANE KATARINA PEREIRA DE AZEVEDO   +5 more
doaj  

Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley   +1 more source

Application of 68Ga‐ and 177Lu‐Labeled FAP Inhibitor in Evaluation and Treatment of Cardiac Fibrosis After Myocardial Infarction

MedComm
68Ga and 177Lu‐labeled fibroblast activation protein inhibitor (FAPI) have been introduced for the diagnosis and treatment of multiple malignant and non‐malignant diseases.
Yiheng Zhao, Xiangyu Su, Boyang Xiang, Shuchen Zhang, Xiang Zhou   +4 more
doaj   +1 more source

Fibroblast Activation Protein Expression Differs Between Inflamed and Fibrostenotic Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
This study demonstrates that fibroblast activation protein expression is elevated in inflamed and fibrostenotic inflammatory bowel disease, with highest levels in fibrostenotic Crohn's disease. Cellular fibroblast activation protein predominates in inflamed tissues and localises to α‐SMA−PDPN−CD90+ stromal cells. ABSTRACT Background Intestinal fibrosis
Dalia A. Lartey, Bram W. van Os, Bo Jun Ke, Kelly van Wijnbergen, Gert de Hertogh, Luuk J. A. C. Hawinkels, Gianluca Matteoli, Jie Su, Christianne J. Buskens, Jarmilla D. W. van der Bilt, Geert R. A. M. D'Haens, Joep Grootjans, Manon E. Wildenberg, Marieke C. Barnhoorn, Mark Löwenberg   +14 more
wiley   +1 more source

Caracterização do Traumatizado Por Acidentes Motociclísticos

UNINGÁ Review, 2017
O trauma é considerado o somatório de abalos causados inesperadamente por um agente físico etiológico de natureza e tamanho variados, podendo se estabelecer diversas partes do corpo.
GRAZIELE DE SOUSA COSTA, KARINNA ALVES AMORIM DE SOUSA, ANA CLAUDIA DE OLIVEIRA SOUSA, JORDÂNIA QUEIROZ REIS, PÉTTERSON DANILO DE OLIVEIRA LIMA GOIANO, MICKAELLE BEZERRA CALAÇA   +5 more
doaj  

Preoperative [68Ga]Ga-FAPI-04 PET for evaluating pathological complete response to neoadjuvant therapy in gastrointestinal adenocarcinoma patients

Frontiers in Immunology
ObjectiveThis study aimed to assess the value of preoperative [68Ga]Ga-FAPI-04 positron emission tomography (PET) for evaluating pathological complete response (pCR) in patients with gastrointestinal adenocarcinomas receiving neoadjuvant therapy (NAT ...
Xiao Zhang, Xiao Zhang, Xiao Zhang, Yuan Feng, Yuan Feng, Yuan Feng, Zhaoguo Lin, Zhaoguo Lin, Zhaoguo Lin, Ranran Chen, Yongkang Gai, Yongkang Gai, Yongkang Gai, Chunxia Qin, Chunxia Qin, Chunxia Qin, Xiaoli Lan, Xiaoli Lan, Xiaoli Lan   +18 more
doaj   +1 more source

Dual‐view scout scans with deep learning for ultra‐low dose attenuation correction in PET

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Accurate attenuation correction (AC) is essential for quantitative positron emission tomography (PET). Conventional CT‐based AC provides reliable attenuation (μ‐) maps but adds radiation, introduces PET/CT misalignment artifacts, and is unavailable on stand‐alone PET systems.
Florence M. Muller, Margaret E. Daube‐Witherspoon, Michael J. Parma, Amy E. Perkins, Peter B. Noël, Christian Vanhove, Stefaan Vandenberghe, Joel S. Karp   +7 more
wiley   +1 more source

Synthesis and Preclinical Evaluation of a Novel FAPI-04 Dimer for Cancer Theranostics

, 2023
Overexpression of fibroblast activation protein (FAP) in cancer-associated fibroblasts in a wide variety of tumors enables a highly selective targeting strategy using FAP inhibitors (FAPIs).
Jun Zhang (48506), Xuan Zhong, Jingru Guo, Rui Yang (293531), Rui Yang, Wenyu Wu, Guoqiang Shao (1918309), Xiuping Han, Xiuping Han (11574238), Jun Zhang, Jingru Guo (4488250), Xuan Zhong (514234), Guoqiang Shao, Wenyu Wu (129369)   +13 more
core   +1 more source

Structure Optimization and Their Biodistribution in Tumor-bearing Mice on FAP and αⅤβ3 Dual Targeting Molecular Probes

Yuanzineng kexue jishu
Fibroblast activation protein (FAP) is a crucial biomarker for the activation of tumor associated fibroblasts, served as an excellent target for both the diagnosis and treatment of cancer.
WU Xiaoming1, 2, TIAN Guoxin3, WEN Xuejun2, 4, HE Tian1, 2, MA Fuqiu1, 3, XUE Yun1, 3
doaj   +1 more source