Results 51 to 60 of about 4,179 (208)

Increased synovial and entheseal fibroblast activation detected by 68Ga-FAPI-PET/CT is associated with the development of psoriatic arthritis in psoriasis patients with arthralgia

RMD Open
Objectives To assess the clinical and imaging characteristics associated with fibroblast activation detected by 68Gallium-labelled fibroblast activation protein inhibitor positron emission tomography/CT (68Ga-FAPI-PET/CT) in patients with psoriasis and ...
Georg Schett, Andreas Ramming, Filippo Fagni, Christian Schmidkonz, Armin Atzinger, Torsten Kuwert, Michael Sticherling, Koray Tascilar, Sara Bayat, Maria Gabriella Raimondo, Melek Yalcin Mutlu, Rita Noversa de Sousa, Giulia Corte, Alp Temiz   +13 more
doaj   +1 more source

Value of [68Ga]Ga‐FAPI‐04 PET imaging in acute coronary syndrome complicated by suspected gastrointestinal malignancies

View, 2023
Early diagnosis of gastrointestinal malignancies in patients with acute coronary syndrome (ACS) is often delayed. The present study aims to demonstrate the value of [68Ga]Ga‐FAPI‐04 PET imaging in ACS with suspected gastrointestinal malignancies.
Mingzhen Ying, Qinqin Yang, Xudong Xu, Shengyong Wu, Wei Yin, Siyu Liang, Guixia Pan, Changjing Zuo, Zhifu Guo, Chao Cheng, Suxuan Liu   +10 more
doaj   +1 more source

Prospective comparison of 68Ga-FAPI-04 and 18F-FDG PET/CT for tumor staging in nasopharyngeal carcinoma

Frontiers in Oncology, 2022
PurposeTo explore the difference in the effectiveness of gallium-68 fibroblast activation protein inhibitor (68Ga-FAPI-04) PET/CT and fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT for the initial staging of patients with nasopharyngeal carcinoma (NPC ...
Haoyuan Ding, Haoyuan Ding, Haoyuan Ding, Haoyuan Ding, Juan Liang, Lin Qiu, Lin Qiu, Lin Qiu, Tingting Xu, Tingting Xu, Tingting Xu, Liang Cai, Liang Cai, Liang Cai, Qiang Wan, Qiang Wan, Qiang Wan, Li Wang, Li Wang, Li Wang, Ya Liu, Ya Liu, Ya Liu, Yue Chen, Yue Chen, Yue Chen, Yue Chen   +26 more
doaj   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

In Situ Self‐Assembled Molecular Fortifying Agent for Enhanced Retention and Therapeutic Efficacy of Radiopharmaceuticals

Aggregate, Volume 7, Issue 10, October 2026.
A molecular‐fortifying agent strategy based on in situ self‐assembly is developed to prolong tumor retention of radioligands. After tumor‐targeting, FAP‐α cleavage triggers nanofiber formation, presenting azide anchors for bioorthogonal capture of pre‐accumulated radioligands.
Daojia Liu, Xiaoqin Luo, Xiaojuan Wang, Xing Liu, Fanglei Zhang, Pan Wang, Jibin Song, Junqiang Chen   +7 more
wiley   +1 more source

Radiosynthesis and in-vitro identification of a molecular probe 131I-FAPI targeting cancer-associated fibroblasts

Frontiers in Oncology
PurposeFibroblast activation protein (FAP) is highly expressed in the mesenchyme of most malignant epithelial tumors, while its expression is low in normal tissues. FAP inhibitors (FAPIs) bind specifically to FAP and are used for tumor-targeted diagnosis
Yaxin Tian, Yaxin Tian, Yanghongyan Jiang, Ping Ma, Xiaowei Ma, Liang Du, Fengkui Wang, Xiaodong Yu, Qian Zhao   +8 more
doaj   +1 more source

Artificial Intelligence in Gastric Cancer: Diagnostic, Prognostic, and Predictive Developments, Evidence Maturity, and Translational Challenges

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gastric cancer (GC) remains a major global health burden characterized by substantial heterogeneity in diagnosis, prognosis, and treatment response. Artificial intelligence (AI), including machine learning (ML) and deep learning (DL), has been increasingly investigated for the analysis of endoscopic images, radiological scans, whole‐
Chong Chen, Weisong Xu, Tong Wu, Junpeng Zhao, Xuebing Xu, Mingbing Xiao, Kang Xu   +6 more
wiley   +1 more source

Localization of Pyelonephritis by 68Ga-FAPI PET CT.

Asia Oceania journal of nuclear medicine & biology, 2023
Fibroblast activation protein inhibitor (FAPI) is a quinoline-based membrane-bound glycoprotein enzyme that is not usually expressed in normal adult tissues, except for the myometrium and sometimes the pancreas. Its expression increases in inflammation and cancer-associated fibroblasts (CAF). As FAPI is a new molecule with a promising future, presented
Rajlaxmi Jagtap, shailendra savale, Gauri Khajindar, Shrikant Solav   +3 more
openaire   +3 more sources

sj-pdf-1-ajs-10.1177_03635465231208843 – Supplemental material for Fibroblast Activation Protein–Targeted PET/CT with Al18F-NODA-FAPI-04 for In Vivo Imaging of Tendon Healing in Rat Achilles Tendon Injury Models

, 2023
Supplemental material, sj-pdf-1-ajs-10.1177_03635465231208843 for Fibroblast Activation Protein–Targeted PET/CT with Al18F-NODA-FAPI-04 for In Vivo Imaging of Tendon Healing in Rat Achilles Tendon Injury Models by Zhenfeng Liu, Haiying Zhou, Pengfei Li ...
Zhenfeng Liu (431113), Xinhui Su (1341387), Yanzhao Dong (13948111), Tian Tu (5899157), Hui Lu (12370), Sohaib Hasan Abdullah Ezzi (14261924), Pengfei Li (290581), Vishnu Goutham Kota (5216144), Mengjie Dong (6396161), Ahmad Alhaskawi (14261918), Yuqiao Huang (11421561), Zewei Wang (2120281), Haiying Zhou (1315533), Mohamed Hasan Abdulla Hasan Abdulla (17414288)   +13 more
core   +1 more source

Contemporary Concise Review 2025: Interstitial Lung Disease

Respirology, Volume 31, Issue 10, Page 974-982, October 2026.
ABSTRACT Multidisciplinary discussion remains the cornerstone of ILD diagnosis and management, with recent advances further strengthening the integration of clinical, radiological, pathological, and molecular information. Updated ILD nomenclature and classification better align disease terminology with underlying morphology and pathobiology.
Tonia Magrì, Luca Richeldi
wiley   +1 more source