Farmacogenômica e Doença Cardiovascular: Onde Estamos e Para Onde Vamos [PDF]
Arquivos Brasileiros de Cardiologia, 2020 Resumo A farmacogenômica (FGx) investiga a interação entre genes e medicamentos. Através da análise de regiões específicas do DNA, informações sobre o perfil de metabolização do paciente para um determinado fármaco podem ser descritas, assim como o ...
Ricardo Stein +3 more
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CYP2C:TG Haplotype in Native Mexicans, Molecular Ancestry and Its Implications for CYP2C19 Genotype–Phenotype Correlation [PDF]
PharmaceuticalsBackground: Recent studies have associated the presence of the CYP2C:TG haplotype with increased metabolism of CYP2C19 substrates such as escitalopram and sertraline, suggesting a potential regulatory interaction between CYP2C18 and CYP2C19.
Carla González de la Cruz +9 more
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Effects of IGF1 rs6214 Polymorphism and Milk Consumption on Serum Levels of IGF-1 and GH and Body Composition [PDF]
MetabolitesMilk and dairy are rich in insulin-like growth factor 1 (IGF-1), a protein secreted through the action of growth hormone (GH) and implicated in growth and metabolism.
Julio Cesar Grijalva-Avila +9 more
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Selección de variantes farmacogenómicas y metodología para su uso en farmacia comunitaria [PDF]
Farmacéuticos ComunitariosLos organismos reguladores, como la Food and Drug Administration (FDA) y la European Medicines Agency (EMA), reconocen la farmacogenética como una herramienta clave en sus guías farmacológicas para el asesoramiento farmacéutico.
Almudena Montero-Gómez +1 more
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PTPN9 regulates HER3 phosphorylation during trastuzumab treatment and loss of PTPN9 is a potential biomarker for trastuzumab resistance in HER2 positive breast cancer. [PDF]
Cancer Commun (Lond)Cancer Communications, Volume 45, Issue 1, Page 68-73, January 2025.
Azad A +15 more
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Rapid Identification of Drug Resistance and Phylogeny in M. tuberculosis, Directly from Sputum Samples [PDF]
Microbiology Spectrum, 2022 Tuberculosis (TB) remains one of the most important infectious diseases globally. Establishing a resistance profile from the initial TB diagnosis is a priority.
Martín Barbosa-Amezcua +10 more
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Farmacogenómica y personalización de tratamientos en obstetricia: Hacia un enfoque más preciso
Revista Internacional de Salud Materno FetalDurante mucho tiempo, las pacientes obstétricas han sido una población marginada en cuanto a los avances médicos farmacológicos debido a las restricciones éticas que limitan su participación en ensayos clínicos.
Daisy Flores-Cortez
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Hematology, Transfusion and Cell Therapy, 2023 Introdução: A anemia falciforme é um desafio significativo para a saúde pública devido à sua crescente prevalência global. A crise vaso-oclusiva é a principal forma de apresentação clínica dessa doença, sendo responsável por cerca de 90% das ...
ACV Almeida +5 more
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The Microbiome as Part of the Contemporary View of Tuberculosis Disease [PDF]
Pathogens, 2022 The study of the microbiome has changed our overall perspective on health and disease. Although studies of the lung microbiome have lagged behind those on the gastrointestinal microbiome, there is now evidence that the lung microbiome is a rich, dynamic ...
Martín Barbosa-Amezcua +3 more
doaj +2 more sources
Utilidad del gen SLCO1B1 como marcador de interés en la farmacogenómica de las estatinas
Revista Colombiana de Cardiología, 2019 Resumen: Las enfermedades cardiovasculares son la principal causa de muerte en el mundo. Fármacos hipolipemiantes como las estatinas son la primera alternativa en la prevención primaria de eventos cardiovasculares, ictus cerebrales y procedimientos de ...
Melissa Robledo +4 more
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