Modulation of Cox-1, 5-, 12- and 15-Lox by popular herbal remedies used in southern Italy against psoriasis and other skin diseases. [PDF]
, 2014 Acanthus mollis (Acanthaceae), Achillea ligustica, Artemisia arborescens and Inula viscosa (Asteraceae) are used in Southern Italy against psoriasis and other skin diseases that occur with an imbalanced production of eicosanoids.
Amenta +26 more
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An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice [PDF]
, 2013 Interleukin (IL)-33, the most recent member of the IL family of cytokines, signals through the ST2 receptor. IL-33/ST2 signaling mediates antigen challenge-induced mechanical hyperalgesia in the joints and cutaneous tissues of immunized mice. The present
Alves-Filho, J.C. +9 more
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História, Ciências, Saúde: Manguinhos, 1996 O presente artigo enfoca a singularidade do pensamento médico de Arnaldo de Vilanova em comparação com o que prevalecia entre seus contemporâneos no continente europeu no século XIII.
Ana Maria Alfonso-Goldfarb +1 more
doaj +1 more source
Algunas consideraciones sobre la enseñanza de la Farmacología en la carrera de Estomatología en Cuba
Edumecentro, 2021 Introducción: la Farmacología constituye el sustento científico de la terapéutica medicamentosa abordada en las asignaturas clínicas en la carrera de Estomatología, lo cual justifica su inclusión en los planes de estudios y pone de manifiesto la ...
Ana Ibis Bosch Nuñez
doaj
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents. [PDF]
, 2008 Following our previous research on anti-inflammatory drugs (NSAIDs), we report here the synthesis of chiral 1,5-diarylpyrroles derivatives that were characterized for their in vitro inhibitory effects toward cyclooxygenase (COX) isozymes.
ANZELLOTTI P. +20 more
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Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]
, 2012 The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco +18 more
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Tratamiento farmacológico de la emergencia Hipertensiva
Medimay, 2014 Se presenta la emergencia hipertensiva desde varios puntos de vista. Se define la entidad, se abordaron las diferentes formas de presentación así como las causas que la producen.
Antonio Ariel Gutiérrez Alvarez +2 more
doaj +4 more sources
Tucumanin, a β-hydroxy-γ-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I [PDF]
, 2004 A new β-hydroxy-γ-methyl-γ-lactone bistetrahydrofuranic acetogenin, tucumanin, with the infrequent symmetrical threo/trans/threo/trans/ threo relative configuration at the tetrahydrofuran rings was isolated from Annona cherimolia (Annonaceae) seeds.
Alvarez, Olga +8 more
core +1 more source
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1:a novel anticancer small-molecule [PDF]
, 2015 Restoration of the p53 pathway, namely by reactivation of mutant (mut) p53, represents a valuable anticancer strategy. Herein, we report the identification of the enantiopure tryptophanol-derived oxazoloisoindolinone SLMP53-1 as a novel reactivator of ...
Bessa, Cláudia +15 more
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Revista Cubana de Medicina Militar, 2023 Introducción: En las investigaciones educativas, la evaluación de la efectividad de resultados científicos resulta necesaria para demostrar que en la práctica pedagógica la nueva propuesta transforma el objeto de estudio.
Ana Ibis Bosch Nuñez +1 more
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