Results 31 to 40 of about 1,274,773 (292)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Misalignment of perceptions with records and resources for responding to climate change risk

open access: yesFrontiers in Climate, 2022
Climate change risks like extreme temperatures and high variability in rainfall adversely affect livelihoods, particularly for farmers in Burkina Faso where the primary sector is agriculture.
Sudha Kannan   +2 more
doaj   +1 more source

Can organic farming help to reduce N-losses? Experiences from Denmark [PDF]

open access: yes, 1998
This study is in two parts. In the first part, nitrogen N)losses per unit of milk and meat in Danish conventional and organic pig and dairy farming were compared on the basis of farm data.
Dalgaard, T.   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Land sharing vs. land sparing for biodiversity: How agricultural markets make the difference : Working Paper N° TSE-435 [PDF]

open access: yes, 2013
We show that between intensive and extensive farming, the production method most beneficial to biodiversity depends on the equilibrium of agricultural markets.
Couvet, Denis   +2 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Empowering Indigenous Farmers with Fish Farming on South Sumatra Peatlands

open access: yesHabitat, 2021
Forest and land fire is mentioned as a main problem of peatlands occurring every year and has provided huge losses for all parties. The research aimed how to empower indigenous farmers with fish farming on South Sumatra peatlands.
Elisa Wildayana, M. Edy Armanto
doaj   +1 more source

Fungi in Danish soils under organic and conventional farming [PDF]

open access: yes, 2004
A multi-soil study was conducted in Denmark including 29 sites, 8 classified as ‘Organic’, 11 as ‘Conventional with manure and synthetic fertilisers’ and 10 as ‘Conventional with synthetic fertilisers’.
Elmholt, S., Labouriau, R.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Farming Differentiation in the Rural-urban Interface of the Middle Mountains, Nepal: Application of Analytic Hierarchy Process (AHP)Modeling [PDF]

open access: yes, 2010
This article investigates the dominant factors of farming differentiation in the rural-urban interface of the densely populated Kathmandu Valley, using the Analytic Hierarchy Process (AHP) modeling. The rural-urban interface in the Kathmandu Valley is
Bhatta, G.D., Doppler, W.
core  

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