Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Misalignment of perceptions with records and resources for responding to climate change risk
Climate change risks like extreme temperatures and high variability in rainfall adversely affect livelihoods, particularly for farmers in Burkina Faso where the primary sector is agriculture.
Sudha Kannan +2 more
doaj +1 more source
Can organic farming help to reduce N-losses? Experiences from Denmark [PDF]
This study is in two parts. In the first part, nitrogen N)losses per unit of milk and meat in Danish conventional and organic pig and dairy farming were compared on the basis of farm data.
Dalgaard, T. +2 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Land sharing vs. land sparing for biodiversity: How agricultural markets make the difference : Working Paper N° TSE-435 [PDF]
We show that between intensive and extensive farming, the production method most beneficial to biodiversity depends on the equilibrium of agricultural markets.
Couvet, Denis +2 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Empowering Indigenous Farmers with Fish Farming on South Sumatra Peatlands
Forest and land fire is mentioned as a main problem of peatlands occurring every year and has provided huge losses for all parties. The research aimed how to empower indigenous farmers with fish farming on South Sumatra peatlands.
Elisa Wildayana, M. Edy Armanto
doaj +1 more source
Fungi in Danish soils under organic and conventional farming [PDF]
A multi-soil study was conducted in Denmark including 29 sites, 8 classified as ‘Organic’, 11 as ‘Conventional with manure and synthetic fertilisers’ and 10 as ‘Conventional with synthetic fertilisers’.
Elmholt, S., Labouriau, R.
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Farming Differentiation in the Rural-urban Interface of the Middle Mountains, Nepal: Application of Analytic Hierarchy Process (AHP)Modeling [PDF]
This article investigates the dominant factors of farming differentiation in the rural-urban interface of the densely populated Kathmandu Valley, using the Analytic Hierarchy Process (AHP) modeling. The rural-urban interface in the Kathmandu Valley is
Bhatta, G.D., Doppler, W.
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