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Fragrance material review on farnesol

Food and Chemical Toxicology, 2008
A toxicologic and dermatologic review of farnesol when used as a fragrance ingredient is presented.
S P Bhatia, C S Letizia, S P Bhatia
exaly   +3 more sources

Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis [PDF]

open access: yesPlant Journal, 2011
SummaryFarnesol, which is toxic to plant cells at high concentrations, is sequentially phosphorylated to farnesyl phosphate and farnesyl diphosphate. However, the genes responsible for the sequential phosphorylation of farnesol have not been identified and the physiological role of farnesol phosphorylation has not been fully elucidated.
A Heather, Fitzpatrick   +2 more
exaly   +3 more sources

Effect of farnesol on Candida dubliniensis morphogenesis [PDF]

open access: yesLetters in Applied Microbiology, 2007
Cell-cell signalling in Candida albicans is a known phenomenon and farnesol was identified as a quorum sensing molecule determining the yeast morphology. The aim of this work was to verify if farnesol had a similar effect on Candida dubliniensis, highlighting the effect of farnesol on Candida spp. morphogenesis.Two different strains of C.
Martins M, Joana Azeredo, Henriques M
exaly   +4 more sources

Metabolism of Farnesol: Phosphorylation of Farnesol by Rat Liver Microsomal and Peroxisomal Fractions

Biochemical and Biophysical Research Communications, 1997
In this study we provide evidence for the first time that rat liver microsomal and peroxisomal fractions are able to phosphorylate free farnesol to its diphosphate ester in a CTP dependent manner. The farnesyl diphosphate (FPP) kinase activity is decreased in whole liver homogenates obtained from rats treated with cholesterol and unchanged in ...
D, Westfall   +3 more
openaire   +2 more sources

Quorum sensing by farnesol revisited

Current Genetics, 2017
Quorum sensing, a form of molecular communication in microbial communities, is relatively well studied in bacterial species, but poorly understood in fungi. Farnesol, a quorum sensing molecule secreted by the opportunistic human pathogenic fungus Candida albicans, was the first quorum sensing molecule described in a eukaryotic organism.
Melanie, Polke, Ilse D, Jacobsen
openaire   +2 more sources

Phosphorylation of Farnesol in Rat Liver Microsomes: Properties of Farnesol Kinase and Farnesyl Phosphate Kinase

Archives of Biochemistry and Biophysics, 1998
As farnesol may serve as a nonsterol endogenous regulator of the mevalonate pathway, the possibility that a kinase specific for its phosphorylation is present in the rat liver was investigated. In the 10,000 g supernatant of rat liver, farnesyl monophosphate was synthesized in the presence of ATP. The Km value for farnesol was 2.3 microM.
Jacob Grünler   +2 more
exaly   +3 more sources

Asymmetric reduction of farnesol

Tetrahedron, 1986
Abstract Asymmetric hydroboration-oxidation followed by reductive deoxygenation has been used to bring about the asymmetric hydrogenation of simple trisubstituted olefins. This technique has been illustrated by the preparation of (R)-(-)-6,7,10,11-tetrahydrofarnesol.
Marc Julia, Pierre Roy
openaire   +1 more source

Preferential induction of apoptosis of leukaemic cells by farnesol [PDF]

open access: yesFEBS Letters, 2000
Farnesol preferentially inhibits proliferation and induces apoptosis of tumour‐derived but not non‐transformed cell lines. We investigated whether farnesol induces apoptosis of blasts from patients with acute myeloid leukaemia (AML) and leukaemic cell lines, as compared with normal, human primary haemopoietic cells.
Charles Marson, N S Thomas
exaly   +4 more sources

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