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Neuropharmacological properties of farnesol in Murine model.
Iranian journal of veterinary research, 2016Research on new compounds of therapeutic value for behavioral disorders has progressed recently. Several studies have reported neuropharmacological activities of plant derived terpenes. Farnesol is a sesquiterpene whose most popular source is fruits but the anxiolytic activity for farnesol is still unknown.
Shahnouri, M. +2 more
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Cardioprotection by Farnesol: Role of the Mevalonate Pathway
Cardiovascular Drugs and Therapy, 2013Farnesol is a key metabolite of the mevalonate pathway and known as an antioxidant. We examined whether farnesol treatment protects the ischemic heart.Male Wistar rats were treated orally with 0.2, 1, 5, and 50 mg/kg/day farnesol/vehicle for 12 days, respectively. On day 13, the effect of farnesol treatment on cardiac ischemic tolerance and biochemical
Szűcs, Gergő +8 more
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Effects of farnesol on the thermotropic behavior of dimyristoylphosphatidylcholine
Chemistry and Physics of Lipids, 1994Differential scanning calorimetry (DSC) and DPH fluorescence anisotropy have been used to investigate the effects of trans-trans farnesol on the physical properties of model membranes and extracted cell lipids. Farnesol was shown to have a significant effect on the gel to liquid-crystal phase transition temperature, the enthalpy of the transition and ...
O P, Bondar, G, Melnykovych, E S, Rowe
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Absence of farnesol in strawberry and hop foliage
Journal of Chemical Ecology, 1982The farnesol content of foliage has been proposed as an indicator of susceptibility to the two-spotted spider mite in various crops. The use of this chemical "marker" was investigated for strawberry and hop varieties. No farnesol was detectable in any of the varieties tested.
F A, Gunson, R F, Hutchins
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Insect Biochemistry and Molecular Biology, 2003
The oxidation of farnesol to farnesal is an important step in insect juvenile hormone (JH) biosynthesis and is mediated by one or more alcohol oxidases located within the minute endocrine gland, the corpus allatum. Because lepidopteran insects have the capacity to produce homologous JH structures, the substrate selectivity of farnesol oxidase was ...
S E, Sen +3 more
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The oxidation of farnesol to farnesal is an important step in insect juvenile hormone (JH) biosynthesis and is mediated by one or more alcohol oxidases located within the minute endocrine gland, the corpus allatum. Because lepidopteran insects have the capacity to produce homologous JH structures, the substrate selectivity of farnesol oxidase was ...
S E, Sen +3 more
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ELECTROPHILE INDUCED CYCLIZATION OF FARNESOL
Chemistry Letters, 1972Abstract The cyclization of farnesol with BF3 etherate in dichloromethane solution afforded α-cedrene, 2-epi-α-cedrene and five new hydrocarbons of muurolane type together with isomeric bisabolenes, α-curcumene and δ-selinene. The structure determination of the new compounds and the formation mechanism of cyclized products are presented.
Yoshimoto Ohta, Yoshio Hirose
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Biosynthesis of 2-cis-farnesol
Journal of the Chemical Society, Chemical Communications, 19732-cis-Farnesol and trichodiene are formed by a cell-free preparation from Trichothecium roseum, from all-trans-farnesyl pyrophosphate with the unexpected loss of a 5,5-3H2-mevalonoid tritium label.
Roger Evans +2 more
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Berichte der deutschen chemischen Gesellschaft, 1913
In der vorhergehenden Abhandlung1) hat Herr Dr. Kerschbaum, Holzminden, als Konstitutionsformel fur das Farnesol diejenige eines aliphatischen Terpenalkohols, Open image in new window aufgestellt.
C. Harries, Reinhold Haarmann
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In der vorhergehenden Abhandlung1) hat Herr Dr. Kerschbaum, Holzminden, als Konstitutionsformel fur das Farnesol diejenige eines aliphatischen Terpenalkohols, Open image in new window aufgestellt.
C. Harries, Reinhold Haarmann
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ω-Hydroxylation of farnesol by mammalian cytochromes P450
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2004Studies have shown that mammalian cytochromes p450 participate in the metabolism of terpenes, yet their role in the biotransformation of farnesol, an endogenous 15-carbon isoprenol, is unknown. In this report, [(14)C]-farnesol was transformed to more polar metabolites by NADPH-supplemented mammalian microsomes.
Andrea E, DeBarber +3 more
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The In vitro Effects of Farnesol and Derivatives on Hymenolepis diminuta
The Journal of Parasitology, 1976Employing an in vitro maintenance system, in which 8-day-old Hymenolepis diminuta survives for 24 hr (Fioravanti and MacInnis, 1976), it was found that farnesol or farnesal supplementation of the medium had no beneficial effects on maintenance and these substances induced necrosis at higher concentrations. Similar experiments utilizing Schiller's (1965)
C F, Fioravanti, A J, MacInnis
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