Results 201 to 210 of about 53,667,156 (250)

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

The impact of bariatric and metabolic surgery on the levels of circulating growth differentiation factor 15 in humans. [PDF]

J Physiol Biochem
Yassuda V, Sequeira B, De Sousa-Coelho AL.   +2 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Long-Term Survival with Daratumumab, Lenalidomide and Dexamethasone in Transplant-Ineligible Newly Diagnosed Multiple Myeloma Patients-A Survey from Two Italian Centers. [PDF]

Diseases
Del Fabro V, Gullo L, Giunta G, Uccello G, Bellofiore C, Lo Faro C, Leotta D, Elia F, Vecchio V, Sorbello C, Consoli U, Romano A, Di Raimondo F, Fazio M, Stagno F, Conticello C.   +15 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

An Integrative Review of Potential Diagnostic Biomarkers for Complex Regional Pain Syndrome. [PDF]

J Clin Med
Lopes R, Santos A, Gomes T, Ribeiro J, Rodrigues I, Paiva B, Nzwalo I, Catamo D, Baco J, Buque H, Botelho M, Pais S, Nzwalo H.   +12 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Moving Toward the Next Generation of HMLS-Testing and Validating the Performances of Second-Generation SLAM Systems Compared to Predecessors. [PDF]

Sensors (Basel)
Teppati Losè L, Rinaudo F, Grasso N, Bonfanti C, Kappes S.   +4 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Early Activation of the Complement System After Brain Death in Clinical Kidney Donation and Transplantation. [PDF]

Transplantation
Knijff LWD, van Essen MF, van der Kooij SW, van Gijlswijk-Janssen DJ, Mulvey JF, Lo Faro ML, Ploeg RJ, van Kooten C.   +7 more
europepmc   +1 more source