Results 81 to 90 of about 53,667,156 (250)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Breve história socioeconómica de Faro [PDF]

, 2019
Como em qualquer grande cidade, a história de Faro é indissociável das atividades económicas que, ao longo dos séculos, fizeram a sua riqueza e garantiram, não apenas a sobrevivência, mas, também, a prosperidade dos seus habitantes.
Lage, Bruno, Carrega, Jorge
core   +1 more source

APPLICATION OF GEOGRAPHIC INFORMATION SYSTEM (GIS) AND MULTICRITERIA DECISION MAKING IN AGRO-CLIMATIC ZONING OF TARABA STATE FOR FARO 44 AND FARO 58 RICE PRODUCTION: APPLICATION OF GEOGRAPHIC INFORMATION SYSTEM (GIS) AND MULTICRITERIA DECISION MAKING IN AGRO-CLIMATIC ZONING OF TARABA STATE FOR FARO 44 AND FARO 58 RICE PRODUCTION

, 2023
CDM) in Agro-Climatic Zoning of Taraba State for rice Production. Climatic variables, RiceYield (FARO 44 and FARO 58 Varieties), Digital Elevation Model (DEM), Land Sat 8 (OLI)images and Soil Texture map were the data used.
Umar, A.S, Martins, I.K, Ezra, A, Adebayo, A. A   +3 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Carta social do concelho de Faro [PDF]

, 2008
O presente documento procura identificar os principais elementos de diagnóstico social do concelho de Faro e propor as linhas estratégicas de ação até ...
Sousa, Vanessa Duarte de, Dias, Nelson
core  

Recensão a “Ossónoba e a moeda antiga do Museu Municipal de Faro”

, 2023
Procura mostrar-se o interesse da obra, de Noé Conejo, “Ossónoba e a moeda antiga do Museu Municipal de Faro”, para o estudo da numismática romana da ...
Encarnação, José d'
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Isolation and Molecular Identification of Plant Growth-Promoting Bacillus subtilis from Rice Rhizosphere in North-Eastern Nigeria

UMYU Scientifica Journal
Background: The use of plant growth-promoting rhizobacteria (PGPR) as biofertilizers offers a sustainable alternative to synthetic inputs in rice cultivation.
Sheriff Wakil, Ismail Yahaya Haruna, Alkali Allamin Ibrahim, Lawan Ngala Adam, Ahmed Abbator   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source