Results 131 to 140 of about 622,986 (383)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Change in the Expression of BAK، FAS، BAX، TNF-A، BCL-2 and Survivin Apoptosis Genes of the Human Breast Adenocarcinoma Cells (MCF-7) by Staphylococcal Enterotoxin B

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introduction: Breast cancer is one of the most prevalent malignancies among women. Patients whose suffering from this condition, as a result of the use of conventional therapies often have a poor response to treatment and the relapse among them is ...
Sara Afzali, Abbas Doosti, Mansour Heidari, Nahid Babaei, Parvaneh Keshavarz   +4 more
doaj  

İslam Mimarîsinde Mezhep Etkisi: Fas Câmileri Örneği

İstem, 2019
İslamiyet’in yaygın olduğu coğrafyaya bakıldığında mimarînin bölgelere göre farklı özellikler gösterdiği görülür. Çünkü bir mimarî eser bulunduğu yerin coğrafî ve iklim özellikleri, tarihçesi, eseri inşa eden toplumun inanç kaideleri, kültürü, gelenek ve
Aziz Doğanay, Sümeyra Ocak
doaj   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Fas Ligand in Pemphigus Sera Induces Keratinocyte Apoptosis through the Activation of Caspase-8 [PDF]

, 2003
Mario Puviani, Alessandra Marconi, Carlo Pincelli, Emanuele Cozzani   +3 more
openalex   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

First arriving signals in layered waveguides. An approach based on dispersion diagrams

, 2016
The first arriving signal (FAS) in a layered waveguide is investigated. It is well known that the velocity of such a signal is close to the velocity of the fastest medium in the waveguide, and it may be bigger than the fastest group velocity given by the
Shanin, Andrey V.
core   +1 more source

FAS Haploinsufficiency Is a Common Disease Mechanism in the Human Autoimmune Lymphoproliferative Syndrome [PDF]

, 2011
Hye Sun Kuehn, Iusta Caminha, Julie E. Niemela, V. Koneti Rao, Joie Davis, Thomas A. Fleisher, João Bosco Oliveira   +6 more
openalex   +1 more source

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

Advanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang   +9 more
wiley   +1 more source

İctihadın Modern Müslüman-Çoğunluklu Ülkelerin Aile Hukuku Reformlarındaki Rolü: Fas Örneği (Doktora Tezi)

ULUM, 2018
Yavuz [Altıntaş], Miyase. İctihadın Modern Müslüman-Çoğunluklu Ülkelerin Aile Hukuku Reformlarındaki Rolü: Fas Örneği. Doktora Tezi, SOAS Londra Üniversitesi, Hukuk ve Sosyal Bilimler Fakültesi Hukuk Anabilim Dalı, İngiltere, 2018.
Miyase Yavuz Altıntaş
doaj