Results 231 to 240 of about 538,057 (302)

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

Circulating fatty acid profiles and risk of pulmonary arterial hypertension: Evidence from a large prospective cohort study. [PDF]

Medicine (Baltimore)
Liu S, Yuan H, Cao J, Cai L, Wang Q, Zhou X.   +5 more
europepmc   +1 more source

Evaluation of Panoramic Acquisition Errors by Predoctoral Dental Students

Journal of Dental Education, EarlyView.
Abstract Objectives Panoramic radiography is commonly used in the management of dental‐alveolar pathology. Novice clinicians are prone to technical errors that diminish the diagnostic quality of radiographs. The objective of this study was to analyze technical errors made during panoramic exposures by third‐year (D3) dental students in order to enhance
Zachary B. Featherstone, Xiaoxi Cui, Wenjian Zhang   +2 more
wiley   +1 more source

Cryoablation for fibroadenoma with liquid nitrogen based system: A retrospective analysis of prospectively collected data. [PDF]

PLoS One
Filipov T, Teutsch B, Vass D, Budinszki B, Hegyi P, Doros A, Forrai G, Deák PÁ.   +7 more
europepmc   +1 more source

Upper Bounds on the Minimum Size of Feedback Arc Set of Directed Multigraphs With Bounded Degree

Journal of Graph Theory, EarlyView.
ABSTRACT An oriented multigraph is a directed multigraph without directed 2‐cycles. Let fas ( D ) $\text{fas}(D)$ denote the minimum size of a feedback arc set in an oriented multigraph D $D$. In several papers, upper bounds for fas ( D ) $\text{fas}(D)$ were obtained for oriented multigraphs D $D$ with maximum degree upper‐bounded by a constant ...
Gregory Gutin, Hui Lei, Anders Yeo, Yacong Zhou   +3 more
wiley   +1 more source

A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T cell signaling and differentiation. [PDF]

J Exp Med
Golec DP, Gazzinelli-Guimaraes PH, Chauss D, Yu K, Nagashima H, Cruz AC, Hill T, Ganesan S, Cannons JL, Perry JK, Nivelo L, Joshi I, Pereira N, Silva Oliveira FM, Zheng Y, Jean Pierre M, Druey KM, Lack JB, Dang EV, Nutman TB, Villarino AV, O'Shea JJ, Afzali B, Schwartzberg PL.   +23 more
europepmc   +1 more source

A MR Fingerprinting Development Kit for Quantitative 3D Brain Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Magnetic resonance fingerprinting (MRF) is an emerging quantitative imaging technique that enables multiparametric tissue characterization, but its adoption has been hindered by the complexity of data acquisition and post‐processing. These technical and implementation challenges have limited its broader clinical deployment.
Rasim Boyacioglu, Thomas Kluge, Guido Buonincontri, Wei‐Ching Lo, Stephan Kannengiesser, Mathias Nittka, Arashdeep Kaur, Andrew Dupuis, Dan Ma, Chaitra Badve, Mark A. Griswold, Yong Chen   +11 more
wiley   +1 more source

Camrelizumab Plus Nab-paclitaxel in Patients with Previously Treated Advanced Urothelial Carcinoma: A Multicenter Phase II Study. [PDF]

Cancer Commun (Lond)
Li H, Chen M, Huang R, Rong Q, Hao J, Zheng Q, Su Y, Shu D, Zhang Y, Yang W, Lei X, Cai Y, Xue C, An X, Shi Y.   +14 more
europepmc   +1 more source

Managing Spectral Intensity Variations With In‐Line Fiber‐Optic High‐Volume Noncontact Raman Probes: A Strategy Exploration

Journal of Raman Spectroscopy, EarlyView.
Robust quantification in noncontact Raman sensing requires dedicated correction of working distance dependent background effects, while laser power variations are readily stabilized using internal reference signals. Chemically relevant Raman intensity can be preserved for bulk composition measurements, under variable laser power and working distance ...
Tiril Aurora Lintvedt, Petter Vejle Andersen, Jens Petter Wold, Nils Kristian Afseth   +3 more
wiley   +1 more source