Results 151 to 160 of about 123,724 (326)

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Engineering donor lymphocytes with Fas ligand protein effectively prevents acute graft-versus-host disease. [PDF]

Blood Adv, 2023
Shrestha P, Turan A, Batra L, Gulen AE, Sun Z, Tan H, Askenasy N, Shirwan H, Yolcu ES.   +8 more
europepmc   +1 more source

Why do defects in the Fas-Fas ligand system cause autoimmunity? [PDF]

, 1997
Takashi Suda, Shigekazu Nagata
openalex   +1 more source

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, EarlyView.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

CD95/Fas ligand mRNA is toxic to cells through more than one mechanism. [PDF]

Mol Biomed, 2023
Haluck-Kangas A, Fink M, Bartom ET, Peter ME.   +3 more
europepmc   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Serum soluble Fas ligand is a severity and mortality prognostic marker for COVID-19 patients. [PDF]

Front Immunol, 2022
Saleki K, Shirzad M, Javanian M, Mohammadkhani S, Alijani MH, Miri N, Oladnabi M, Azadmehr A.   +7 more
europepmc   +1 more source

Contribution of Fas ligand to T cell-mediated hepatic injury in mice [PDF]

, 1997
Ken‐ichiro Seino, Nobuhiko Kayagaki, Kazuyoshi Takeda, Katashi Fukao, Ko Okumura, Hideo Yagita∥   +5 more
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

The role of Fas ligand protein in the oxidative stress induced by azoxymethane on crypt colon of rats [PDF]

, 2010
Luiz Antonio Maksoud Bussuan, Djalma José Fagundes, Guido Marks, Priscila Maksoud Bussuan, Roberto Teruya   +4 more
openalex   +1 more source