Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping. [PDF]
Contreras-Ochoa CO +7 more
europepmc +1 more source
Regulation of fas ligand expression by vascular endothelial growth factor in endometrial stromal cells in vitro [PDF]
Murat Berkkanoğlu +4 more
openalex +1 more source
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao +8 more
wiley +1 more source
Fas ligand and the fate of antitumour cytotoxic T lymphocytes
Joe O’Connell
openalex +1 more source
Mitochondrial quality control (MQC) impairment plays a central role in driving the pathogenesis of metabolism‐associated steatotic liver disease (MASLD). Specifically, this is manifested as reduced mitophagy; increased mitochondrial fission and decreased fusion; and impaired mitochondrial biogenesis.
Wenkai Fu +8 more
wiley +1 more source
Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis
The transmembrane death receptor Fas transduces apoptotic signals upon binding its ligand, FasL. Although Fas is highly expressed in cancer cells, insufficient cell surface Fas expression desensitizes cancer cells to Fas-induced apoptosis.
Mehmet H. Kural +12 more
doaj +1 more source
Expression profiling of genes in rheumatoid fibroblast-like synoviocytes regulated by Fas ligand via cDNA microarray analysis. [PDF]
Fukuda K +5 more
europepmc +1 more source
Direct Binding of Fas-associated Death Domain (FADD) to the Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptor DR5 Is Regulated by the Death Effector Domain of FADD [PDF]
Lance R. Thomas +4 more
openalex +1 more source
Human FASTK preferentially binds single‐stranded and G‐rich RNA
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak +7 more
wiley +1 more source
Disruption of fas-fas ligand signaling, apoptosis, and innate immunity by bacterial pathogens. [PDF]
Adam J Caulfield, Wyndham W Lathem
doaj +1 more source

