Results 111 to 120 of about 58,729 (255)

The role of soluble FMS-like tyrosine kinase (sFLT1) and FAS associated proteins in pregnancies complicated by preeclampsia and intrauterine growth restriction (IUGR).

, 2005
PhDCurrent thinking suggests that preeclampsia is associated with activation of the maternal vascular endothelium in response to factors released from the placenta due to placental hypoxia.
Fayyad, Abdalla Mustafa
core  

Estrous cycle dependent changes in expression and distribution of Fas, Fas ligand, Bcl-2, Bax, and pro- and active caspase-3 in the rat ovary

, 2006
In the present investigation, the localization of proteins involved in ovarian apoptosis were studied throughout the estrous cycle in the presence of fluctuating hormone levels.
Voorendt, M., de Boer-Brouwer, M., Slot, K.A., Teerds, K.J., van Vugt, H.H.   +4 more
core   +1 more source

Monocarboxylate transporter 8 modulates the viability and invasive capacity of human placental cells and fetoplacental growth in mice [PDF]

, 2013
Monocarboxylate transporter 8 (MCT8) is a well-established thyroid hormone (TH) transporter. In humans, MCT8 mutations result in changes in circulating TH concentrations and X-linked severe global neurodevelopmental delay.
Laurence S Loubière, Visser, Theo, Whitley G.S., Elisavet Vasilopoulou (420760), Loubière Laurence S., Darras, V.M. (Veerle), Loubière L.S., Darras, VM, Kilby, MD, Trajkovic-Arsic, M. (Marija), Christopher J McCabe, Guy S Whitley, Heike Heuer (420762), Heuer, H, Marija Trajkovic-Arsic, Guy S. Whitley (420764), Visser T.J., McCabe, Christopher, Gendie E. Lash (420763), Visser Theo J., Theo J. Visser (280338), Marija Trajkovic-Arsic (155746), Kilby, Mark, Franklyn, J.A. (Jayne), Mark D. Kilby (420766), Loubière, LS, Trajkovic-Arsic, M, Lash G.E., Loubière, L.S. (Laurence), Whitley Guy S., Darras, Veerle, Jayne A Franklyn, Christopher J. McCabe (420765), Loubière, Laurence, Heuer Heike, Darras V.M., Jayne A. Franklyn (236549), Whitley, Guy, Lash, G.E. (Gendie), Franklyn, Jayne, Gendie E Lash, Whitley, GS, Vasilopoulou, E, McCabe, CJ, Franklyn Jayne A., Franklyn J.A., Shiao Y Chan, Visser, TJ, Chan, SY, Veerle M Darras, Chan, Shiao, Elisavet Vasilopoulou, Heuer H., Vasilopoulou, Elisavet, Vasilopoulou Elisavet, Heuer, Heike, Lash Gendie E., Visser, T.J. (Theo), Heike Heuer, Shiao Y. Chan (420767), McCabe, C.J. (Christopher), Lash, GE, Chan S.Y., Vasilopoulou, E. (Elisavet), Kilby, M.D. (Mark), Trajkovic-Arsic M., Veerle M. Darras (104459), Heuer, H. (Heike), Chan, S.Y. (Shiao), Laurence S. Loubière (420761), McCabe Christopher J., Whitley, G.S. (Guy), Mark D Kilby, Darras Veerle M., McCabe C.J., Trajkovic-Arsic, Marija, Kilby Mark D., Franklyn, JA, Trajkovic-Arsic Marija, Chan Shiao Y., Lash, Gendie, Vasilopoulou E., Theo J Visser, Kilby M.D.   +83 more
core   +1 more source

The Transcription Factor EGR2 Plays a Central Role in the Expansion and Function of TCRαβ+CD4−CD8− Double Negative T Cells in lpr Lupus Mice

Immunology, EarlyView.
The highly expanded TCRβ+ DNT cells in autoimmune‐prone B6/lpr mice are phenotypically and functionally different from the TCRβ+DNT cells of normal B6 mice. Conditional Egr2 deletion in B6/lpr mice not only reduces TCRβ+ DNT cell numbers but also tends to correct the phenotypic and functional abnormalities of DNT cells in B6/lpr mice. In addition, Egr2
Rujuan Dai, Zhuang Wang, Bettina Heid, Christopher M. Reilly, S. Ansar Ahmed   +4 more
wiley   +1 more source

Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways

International Journal of Medical Sciences, 2006
As we previously demonstrated in human hepatocellular carcinoma (HepG2) cells, ethanol at low concentration triggers the Fas apoptotic pathway. However, its role in other intracellular signaling pathways remains unknown. Therefore, the aim of the present
Francisco Castaneda, Sigrid Rosin-Steiner
doaj  

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice

, 2005
Background: Although previous studies have shown that the hepatic sympathetic nerve controls various physiological functions in the liver, the role of this nerve in liver injury has yet to be clarified.Aims: The purpose of this study was to elucidate the
Chida, Y, Takaki, A, Kubo, C, Sudo, N
core  

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Apoptosis and apoptosis-related proteins (Fas, Fas ligand, Blc-2, p53) in lymphoid elements of human ovarian tumors.

European journal of gynaecological oncology, 2000
Different types of lymphocytes have different roles in tumor suppression. Thus, their expression of apoptosis-related proteins (ARP - Fas and Fas ligand, bcl-2, p53) in lymphocytes and their apoptosis were analyzed immunohistochemically in ovarian tumors of different grades.
H, Ben-Hur, P, Gurevich, M, Huszar, A, Ben-Arie, V, Berman, Y, Tendler, O, Zinder, R, Tchanishev, S, Gershon, G, Mor, Y, Zaltsman, F, Kohen, I, Zusman   +12 more
openaire   +1 more source