Results 121 to 130 of about 58,729 (255)
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Combined effects of 17β-estradiol and exercise training on cardiac apoptosis in ovariectomized rats.
PLoS ONE, 2018 BACKGROUND:The purpose of this study was to investigate the combined 17β-estradiol (E2) and exercise training on cardiac pro-survival and anti-apoptotic pathways in ovariectomized rats.
Yi-Yuan Lin +9 more
doaj +1 more source
Radiation and stress-induced apoptosis: A role for Fas/Fas ligand interactions
, 1997 The lpr gene encodes a defective form of Fas, a cell surface protein that mediates apoptosis. This defect blocks apoptotic deletion of autoreactive T and B cells, leading to lymphoproliferation and lupus-like autoantibody production.
Kenrick Maynor +11 more
core +1 more source
Understanding exosomes in diabetic wound healing
Periodontology 2000, EarlyView.Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
Fas ligand interacting proteins : new insights into complex signaling networks [PDF]
, 2005 The Fas ligand is a death factor and a potential signal transducer. Here we show the retrograde signaling of FasL could be demonstrated in human T cells. FasL engagement results in a severe block of T cell activation without increased cell death. In cytotoxic T cells, NK cells , FasL can be located intracellularly in 'secretory lysosomes' and delivered
openaire
European journal of gynaecological oncology, 2001 We studied some of the morphological and immunohistochemical parameters of lichen sclerosus (LS) and carcinomas of the vulva in order to verify some characteristics in LS related to neoplasm transformation. Parameters such as proliferating index, rate of proliferation of lymphoid elements into a tumor and types of such elements were studied.
H, Ben-Hur +4 more
openaire +1 more source
Theileria parva-transformed T cells show enhanced resistance to Fas/Fas ligand-induced apoptosis
, 2003 Lymphocyte homeostasis is regulated by mechanisms that control lymphocyte proliferation and apoptosis. Activation-induced cell death is mediated by the expression of death ligands and receptors, which, when triggered, activate an apoptotic cascade ...
Schneider, P +2 more
core
Characterisation and ontogeny of natural killer cells in Xenopus laevis [PDF]
, 2002 The initial aim of the work described in this Thesis was to investigate the lymphoid organ distribution, phenotype and function of the lymphocyte population identified by candidate anti-Xenopus natural killer (NK) cell monoclonal antibodies (mAb's ...
Stewart, Rebecca
core
Transfusion, EarlyView.Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa +20 more
wiley +1 more source
Fas ligand-induced apoptosis as a mechanism of immune privilege
, 1995 The eye is a privileged site that cannot tolerate destructive inflammatory responses. Inflammatory cells entering the anterior chamber of the eye in response to viral infection underwent apoptosis that was dependent on Fas (CD95)-Fas ligand (FasL) and ...
Thomas Brunner +9 more
core +1 more source