Results 221 to 230 of about 185,643 (306)

Signal and Contrast Optimization With Predicted Excitations (SCOPE) for Accelerating Large FOV Body Imaging at UHF

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Large FOV turbo‐spin‐echo (TSE) imaging at ultra‐high field (UHF) remains challenging due to B1+ inhomogeneity and peak specific absorption rate (pSAR) limitations. This work presents a new time‐interleaved acquisition of modes (TIAMO) framework called SCOPE (Signal and Contrast Optimization with Predicted Excitations), which overcomes
Tobey D. Haluptzok, Simon Schmidt, Gregory J. Metzger   +2 more
wiley   +1 more source

Gustatory avoidance of fatty acids by <i>Aedes aegypti</i> depends on an arthropod-specific TRP channel. [PDF]

Proc Natl Acad Sci U S A
Dhakal S, Bontempo AE, Singh R, Dhavan P, Montell C.   +4 more
europepmc   +1 more source

Physics‐Guided Neural Network for Quantitative Parameter Mapping Using Balanced Steady State Free Precession MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose a new method using a physics‐guided neural network for quantitative parameter mapping in balanced steady‐state free precession (bSSFP) imaging. Theory and Methods We trained physics‐guided neural networks with a multilayer perceptron using simulated bSSFP signals generated from tissue parameters (T1$$ {T}_1 $$, T2$$ {T}_2 $$,
Hye‐Ryeong Choi, Huan Minh Luu, Sung‐Hong Park   +2 more
wiley   +1 more source

Screening and verification of drugs targeting myocardial ischemia-reperfusion injury. [PDF]

Medicine (Baltimore)
Liu Q, Tian Z, Mi S, Liang Z, Hang B.
europepmc   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

Obesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand, Camille Le Cudennec, Estelle Grasset, Natalia Breyner, Claire Bigot, Pierre Dillard, Thierry Sulpice   +6 more
wiley   +1 more source

Autoimmune lymphoproliferative syndrome in Boerboel dogs: clinicopathologic, diagnostic, and genetic characterization. [PDF]

J Vet Intern Med
Tong LJ, Friedenberg SG, Cullen JN, Hamsher H, Minor KM, Furrow E, Vernau W, Horgan L, Stayt J, Hespel A, Reppas G, Malik R.   +11 more
europepmc   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Endothelial Cell Regulation of Lipid Uptake During Feeding and Fasting. [PDF]

Arterioscler Thromb Vasc Biol
Goldberg IJ, Tirumalasetty M, Peche VS, Gaballa R, Cabodevilla AG, Komack M, Miao QR, Abumrad NA.   +7 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

Lipids in kidney diseases: from systemic imbalance to intrarenal alterations of cellular lipid metabolism in rare and common kidney diseases. [PDF]

J Mol Med (Berl)
Garavaglia C, Ossoli A, Gomaraschi M.
europepmc   +1 more source