Results 91 to 100 of about 61,337 (245)

Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL) [PDF]

, 1998
Fas ligand is a type II transmembrane protein which can induce apoptosis in Fas-expressing cells. Recent reports indicate that expression of FasL in transplanted cells may cause graft rejection and, on the other hand, tumor cells may lose their ...
Bilbao, R. (Roberto), Drozdzik, M. (Marek), Lasarte, J.J. (Juan José), Prieto, J. (Jesús), Qian, C. (Cheng)   +4 more
core  

Surface Tethered Epidermal Growth Factor Protects Proliferating and Differentiating Multipotential Stromal Cells from FasL-Induced Apoptosis [PDF]

, 2012
Multipotential stromal cells or mesenchymal stem cells (MSCs) have been proposed as aids in regenerating bone and adipose tissues, as these cells form osteoblasts and adipocytes.
Blair, Harry, Griffith, Linda G., Rodrigues, Melanie, Stockdale, Linda, Wells, Alan   +4 more
core   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

NFAT3-FasL axis synchronously regulates apoptosis and necroptosis in murine cochlear outer hair cells after noise trauma

Frontiers in Molecular Neuroscience
Existing studies have indicated that noise induces apoptosis and necroptosis in cochlear outer hair cells (OHCs). However, the role of the extrinsic cell death pathway, initiated by death ligands in the cochlea, remains unknown.
Wenlun Wang, Wenlun Wang, Wenlun Wang, Lisheng Yu, Shichang Li, Lin Han, Hongwei Zheng   +6 more
doaj   +1 more source

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source

The In Situ Hybridization Expression of Fas and Fas Ligand (FasL) in Trophoblastic tissue of Aborted Women Compared with Normal Pregnancy.

مجلة كلية الطب, 2009
Background: Estimation of the in situ expression of Fas and Fas ligand (FasL) in aborted women compared with normal human pregnancy . Patients and Methods: A technique utilizing in situ hybridization(ISH) was performed to detect and determine the in situ
Amal H. Salman, Dalya B. Hana, Dhamraa W. Ahmad   +2 more
doaj   +1 more source

Tissue Inhibitor of Metalloproteinase–3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells [PDF]

, 2018
Over expression of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in vascular smooth muscle cells (VSMCs) induces apoptosis and reduces neointima formation occurring after saphenous vein interposition grafting or coronary stenting.
Baker, Andrew H., Bennett, Martin R., English, William R., Ireland-Zecchini, Heather, Littlewood, Trevor D., Murphy, Gillian   +5 more
core   +4 more sources

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Human B cell-derived lymphoblastoid cell lines constitutively produce Fas ligand and secrete MHCII+FasL+ killer exosomes

Frontiers in Immunology, 2014
Immune suppression mediated by exosomes is an emerging concept with potentially immense utility for immunotherapy in a variety of inflammatory contexts, including allogeneic transplantation. Exosomes containing the apoptosis-inducing molecule Fas ligand (
Matthew W. Klinker, Matthew W. Klinker, Vincent eLizzio, Tamra J Reed, David A. Fox, David A. Fox, Steven K. Lundy, Steven K. Lundy   +7 more
doaj   +1 more source

Ministry emphasises quality of medical training [PDF]

, 2002
One proposed mechanism of tumour escape from immune surveillance is tumour up-regulation of the cell surface ligan FasL, whichcan lead to apoptosis of Fas receptor (Fas) positive lymphocytes.
Fish, Reginald G., Sherratt, Jonathan A., Webb, Steven D.   +2 more
core   +2 more sources