Results 101 to 110 of about 35,096 (229)
Acta Cirúrgica Brasileira, 2010 PURPOSE: To study the protein Fas ligand (FasL) on the expression of apoptosis, using a model of oxidative stress induced by azoxymethane (AOM), in the crypt of colon in rats.
Luiz Antonio Maksoud Bussuan +4 more
doaj +1 more source
Improvement of FasL Gene Therapy In Vitro by Fusing the FasL to Del1 Protein Domains
, 2011 Gene delivery, transfection, cytotoxicity, and many other factors influence the ability of gene therapy to treat cancer. In addition, as with pharmacologic agents, longer exposure to higher concentrations of gene products should intensify their effects (Wada et al., 2007). Cytotoxic gene products, such as FasL and TRAIL, may remain in tissues after the
Hisataka Kitano +2 more
openaire +2 more sources
The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity
MedComm, Volume 7, Issue 7, July 2026.Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng +3 more
wiley +1 more source
Frontiers in Physiology, 2019 Background: Circulating apoptotic signals (CASs) have been described in the pathologies associated with dysregulated apoptosis, such as cancer, heart diseases, and pulmonary hypertension (PH).
Djuro Kosanovic +18 more
doaj +1 more source
Description and characterization of the chimeric human FasL-derived constructs
, 2013 Panel A: Schematic representation of soluble FasL (sFasL), Flag-tagged sFasL (sfFasL), polymeric Flag-tagged soluble FasL (pfFasL), polymeric TCR γ4 and δ5 Flag-tagged soluble FasL generating the TCR-pfFasL upon cotransfection, and beta2-microglobulin ...
Julie Dechanet-Merville (290088) +5 more
core +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host
Reviews in Medical Virology, Volume 36, Issue 4, July 2026.ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini +4 more
wiley +1 more source
Killer B Lymphocytes and their Fas Ligand Positive Exosomes as Inducers of Immune Tolerance
Frontiers in Immunology, 2015 Induction of immune tolerance is a key process by which the immune system is educated to modulate reactions against benign stimuli such as self-antigens and commensal microbes.
Steven Karl Lundy +4 more
doaj +1 more source
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
Environmental Toxicology, Volume 41, Issue 7, Page 416-458, July 2026.ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, Volume 293, Issue 13, Page 3717-3757, July 2026.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source