Evolutionary regulation of human Fas ligand (CD95L) by plasmin in solid cancer immunotherapy
Despite sharing >98% genomic similarity, humans are more likely to develop cancers than our closest living ancestors, the nonhuman primates. Here, we unexpectedly discover that, unlike chimpanzee and other primates, a critical embryonic development ...
Brice E. N. Wamba +10 more
doaj +1 more source
Expression of FasL in Proliferation of Retinoblastoma Cells: A Mechanism Fas Counterattack
Purpose: The aim of this study were to determine the association of increasing of FasL with increasing proliferation of retinoblastoma cells. Materials and Methods: The protein expression was analyzed in 30 retinoblastoma samples from paraffin block ...
Hendrian Dwikoloso Soebagjo +3 more
doaj
Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis. [PDF]
Schmidt MF +10 more
europepmc +2 more sources
The Role of Inflammatory Biomarkers in Disease Severity and Treatment Response across Psoriasis, Atopic Dermatitis, and Hidradenitis Suppurativa-A Narrative Review. [PDF]
Lewandowska JA, Owczarczyk-Saczonek A.
europepmc +1 more source
Estrogen and progesterone-mediated differential modulation of CD4<sup>+</sup> T-cell pathogenicity in rheumatoid arthritis. [PDF]
Jha R +9 more
europepmc +1 more source
Soluble TIM-3 and galectin-9 serve as additional diagnostic biomarkers in primary central nervous system lymphoma. [PDF]
Nishii S +13 more
europepmc +1 more source
Decoding TNF receptor superfamily control of CD4<sup>+</sup>Foxp3<sup>+</sup> Regulatory T cell-mediated tolerance: implications for the treatment of graft‑versus‑host disease. [PDF]
Chou CK +9 more
europepmc +1 more source
The Trifecta of Polo-Like Kinases, Cancer, and the Immune System: Emerging Intersections and Therapeutic Insights. [PDF]
Jaiswal T +5 more
europepmc +1 more source
A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T cell signaling and differentiation. [PDF]
Golec DP +23 more
europepmc +1 more source
Integration of intragraft transcriptomics and urinary cytokines identifies CXCL10 and FasL signature in subclinical acute rejection. [PDF]
Cox SN +13 more
europepmc +1 more source

