Results 111 to 120 of about 37,208 (191)
The highly expanded TCRβ+ DNT cells in autoimmune‐prone B6/lpr mice are phenotypically and functionally different from the TCRβ+DNT cells of normal B6 mice. Conditional Egr2 deletion in B6/lpr mice not only reduces TCRβ+ DNT cell numbers but also tends to correct the phenotypic and functional abnormalities of DNT cells in B6/lpr mice. In addition, Egr2
Rujuan Dai +4 more
wiley +1 more source
ABSTRACT Interleukin (IL)‐10‐producing B cells represent an archetype for the regulatory functions of B cells. Here, we review the cell‐surface receptors and transcriptional regulators that control IL‐10 expression in B cells and enable their regulatory function in vivo.
Bui Thi Cuc +4 more
wiley +1 more source
Meng Wang,1,* Zheng Wang,2,* Xi-Jing Wang,1 Tian-Bo Jin,3 Zhi-Ming Dai,4 Hua-Feng Kang,1 Hai-Tao Guan,1 Xiao-Bin Ma,1 Xing-Han Liu,1 Zhi-Jun Dai1 1Department of Oncology, Second Affiliated Hospital of Xi’an Jiaotong University, 2Department of ...
Wang M +9 more
core
Altered expression of the Fas ligand (FasL)/Fas ratio exhibits a direct impact on the prognosis of cancer patients, and its impairment in cancer cells may lead to apoptosis resistance.
Rahul Sharma +8 more
core +1 more source
Glucuronyl Glucosyloleanolate: A Safe and Potent AI‐Discovered Depigmenting Saponin
ABSTRACT Purpose Saponins are amphiphilic glycosides found in plants. They have long been used in traditional Asian remedies for their anti‐inflammatory, protective, and rejuvenating properties. One representative, Glucuronyl Glucosyloleanolate (GGO), was recently discovered using a combination of artificial intelligence and experimental testing as a ...
Yannick Quesnel, Michael Gold
wiley +1 more source
DcR3 Fc administration inhibited FasL-induced apoptosis.
DcR3 Fc administration decreased human peripheral lymphocyte apoptosis induced by FasL. Peripheral lymphocytes cells were obtained from septic shock patients using Ficoll-Paque Plus and randomly divided into four groups: control, FasL-induced, FasL plus ...
DongYu Liang (762413) +3 more
core +1 more source
DAC enhances FASL-mediated cell death of GL261 glioma cells.
(A) GL261-OVA GDC (GDC) and GL261-OVA GIC (GIC) FASL-mediated cell death normalised to untreated controls, measured by 7AAD staining. Cells were treated 48h with 10 μM DAC and then plated for 20h with increasing concentrations of the multimeric FASL or ...
Serena Pellegatta (109687) +13 more
core +1 more source
原发性胆汁性肝硬化患者肝组织和外周血单个核细胞Fas、FasL的检测
目的通过原发性胆汁性肝硬化患者肝组织和外周血单个核细胞Fas、FasL的表达,探讨Fas、FasL在原发性胆汁性肝硬化患者发病机制中的作用。方法应用免疫组织化学技术,以兔抗Fas及兔抗FasL多克隆抗体,对20例原发性胆汁性肝硬化(PBC)患者肝组织和外周血单个核细胞中的Fas、FasL进行检测。结果18例PBC患者外周血单个核细胞检出Fas、FasL,检出率均为90%,Fas、FasL平均阳性细胞数分别为62%、59%。20例PBC患者16例Fas阳性颗粒表达于肝细胞胞浆,4例表达于肝细胞胞膜 ...
刘妍 +7 more
doaj
The majority of FasL+ splenocytes are B cells.
Splenocytes from naïve mice were stained for surface expression of FasL and the cellular composition of FasL− and FasL+ subsets was examined by flow cytometry.
David A. Fox (441429) +3 more
core +1 more source
This protocol describes an ELISAassay for measurement of FAS ligand (FASL, CD95L)insupernatants collected from T cell dependent cytotoxicity (TDCC) cultures after BiTE® treatment.
not provided Gordon Moody +7 more
core +1 more source

