Results 111 to 120 of about 35,096 (229)

Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
Integrated physical and virtual modeling provides a scalable framework to overcome sample scarcity, recapitulate mucosal melanoma biology, and accelerate translational discovery toward precision medicine. ABSTRACT Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct ...
Xiangjie Jin, Yuhan Zhang, Yuantai Zhu, Zhiyuan Zhang, Chaoji Shi   +4 more
wiley   +1 more source

Endoteelin FasL imusolmukkeissa ja suoliston imukudoksissa

, 2016
The function of the transmembrane protein FasL is to complex with the Fas receptor in a target cell and induce target cell apoptosis. Fas/FasL-mediated apoptosis plays important role in immunoregulation.
Kokkonen, Tuomo
core  

Distinct role of the Fas rs1800682 and FasL rs763110 polymorphisms in determining the risk of breast cancer among Han Chinese women

, 2016
Meng Wang,1,* Zheng Wang,2,* Xi-Jing Wang,1 Tian-Bo Jin,3 Zhi-Ming Dai,4 Hua-Feng Kang,1 Hai-Tao Guan,1 Xiao-Bin Ma,1 Xing-Han Liu,1 Zhi-Jun Dai1 1Department of Oncology, Second Affiliated Hospital of Xi’an Jiaotong University, 2Department of ...
Wang M, Dai ZJ, Liu XH, Dai ZM, Kang HF, Guan HT, Wang Z, Wang XJ, Jin TB, Ma XB   +9 more
core  

A Fas Ligand (FasL)-Fused Humanized Antibody Against Tumor-Associated Glycoprotein 72 Selectively Exhibits the Cytotoxic Effect Against Oral Cancer Cells with a Low FasL/Fas Ratio

, 2017
Altered expression of the Fas ligand (FasL)/Fas ratio exhibits a direct impact on the prognosis of cancer patients, and its impairment in cancer cells may lead to apoptosis resistance.
Rahul Sharma, Ming-Hsien Chien, Wei-Jiunn Lee, Tsung-Ching Lai, Wei-Min Chang, Michael Hsiao, Yu-Chan Chang, Derek V. Chan, Yuan-Feng Lin   +8 more
core   +1 more source

Expression of Fas and FasL in Trophoblastic Tissue of Women with Spontaneous and Induced Abortion Using insitu Hybridization Technique

The Iraqi Journal of Medical Sciences, 2016
Background:Apoptosis of trophoblastic cells may play a role in the pathogenesis of abortion, and one mechanism of apoptosis is Fas receptor and legand system.
Mohammed R Ali, Abdul-Razzak H Ahmed
doaj   +2 more sources

D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

Scientific Reports, 2017
This study was designed to explore the protective effect of D4F, an apolipoprotein A-I mimetic peptide, on nuclear factor-κB (NF-κB)-dependent Fas/Fas ligand (FasL) pathway-mediated apoptosis in macrophages induced by oxidized low-density lipoprotein (ox-
Hua Tian, Shu-tong Yao, Na-na Yang, Jie Ren, Peng Jiao, Xiangjian Zhang, Dong-xuan Li, Gong-an Zhang, Zhen-fang Xia, Shu-cun Qin   +9 more
doaj   +1 more source

Role of Fas/FasL in Systemic Candidiasis [PDF]

The Journal of Infectious Diseases, 2000
Ashman, RB, Mullbacher, A, Papadimitriou, JM   +2 more
openaire   +5 more sources

Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils.

, 2016
BACKGROUND In contrast to eosinophils and neutrophils, the regulation of the lifespan of human basophils is poorly defined, with the exception of the potent anti-apoptotic effect of IL-3 that also promotes pro-inflammatory effector functions and ...
Hagmann, B R, Kaufmann, Thomas, Fux, Michaela, B. R. Hagmann, T. Kaufmann, C. A. Dahinden, M. Fux, Odermatt, A, A. Odermatt, Dahinden, C A   +9 more
core   +1 more source

DcR3 Fc administration inhibited FasL-induced apoptosis.

, 2015
DcR3 Fc administration decreased human peripheral lymphocyte apoptosis induced by FasL. Peripheral lymphocytes cells were obtained from septic shock patients using Ficoll-Paque Plus and randomly divided into four groups: control, FasL-induced, FasL plus ...
DongYu Liang (762413), XiaoLi Lou (762414), HongWei Chen (5664157), YanQiang Hou (5664154)   +3 more
core   +1 more source

The majority of FasL⁺ splenocytes are B cells.

, 2013
Splenocytes from naïve mice were stained for surface expression of FasL and the cellular composition of FasL− and FasL+ subsets was examined by flow cytometry.
David A. Fox (441429), Matthew W. Klinker (441427), Tamra J. Reed (441428), Steven K. Lundy (441430)   +3 more
core   +1 more source