Results 121 to 130 of about 35,096 (229)
, 2017 This protocol describes an ELISAassay for measurement of FAS ligand (FASL, CD95L)insupernatants collected from T cell dependent cytotoxicity (TDCC) cultures after BiTE® treatment.
not provided Gordon Moody +7 more
core +1 more source
原发性胆汁性肝硬化患者肝组织和外周血单个核细胞Fas、FasL的检测
Zhongguo shiyan zhenduanxue, 2007 目的通过原发性胆汁性肝硬化患者肝组织和外周血单个核细胞Fas、FasL的表达,探讨Fas、FasL在原发性胆汁性肝硬化患者发病机制中的作用。方法应用免疫组织化学技术,以兔抗Fas及兔抗FasL多克隆抗体,对20例原发性胆汁性肝硬化（PBC）患者肝组织和外周血单个核细胞中的Fas、FasL进行检测。结果18例PBC患者外周血单个核细胞检出Fas、FasL,检出率均为90%,Fas、FasL平均阳性细胞数分别为62%、59%。20例PBC患者16例Fas阳性颗粒表达于肝细胞胞浆,4例表达于肝细胞胞膜 ...
刘妍 +7 more
doaj
, 2012 International audienceMembrane FasL is the natural trigger of Fas-mediated apoptosis. A soluble homotrimeric counterpart (sFasL) also exists which is very weakly active, and needs oligomerization beyond its trimeric state to induce apoptosis. We recently
Julie Dechanet-Merville (290088) +17 more
core +1 more source
DAC enhances FASL-mediated cell death of GL261 glioma cells.
, 2016 (A) GL261-OVA GDC (GDC) and GL261-OVA GIC (GIC) FASL-mediated cell death normalised to untreated controls, measured by 7AAD staining. Cells were treated 48h with 10 μM DAC and then plated for 20h with increasing concentrations of the multimeric FASL or ...
Serena Pellegatta (109687) +13 more
core +1 more source
Endothelial FasL in lymph nodes and in intestinal lymphatic tissue
, 2016 The function of the transmembrane protein FasL is to complex with the Fas receptor in a target cell and induce target cell apoptosis. Fas/FasL-mediated apoptosis plays important role in immunoregulation.
Kokkonen, T. (Tuomo)
core
Evolutionary regulation of human Fas ligand (CD95L) by plasmin in solid cancer immunotherapy
Nature CommunicationsDespite sharing >98% genomic similarity, humans are more likely to develop cancers than our closest living ancestors, the nonhuman primates. Here, we unexpectedly discover that, unlike chimpanzee and other primates, a critical embryonic development ...
Brice E. N. Wamba +10 more
doaj +1 more source
, 2002 It has been suggested that over-expression of FasL could provide immune-privileged sites where transfected genes or/and grafted cells could exert their therapeutic action without inducing an immune response.
PAMPINELLA F +7 more
core
Expression of FasL in Proliferation of Retinoblastoma Cells: A Mechanism Fas Counterattack
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014 Purpose: The aim of this study were to determine the association of increasing of FasL with increasing proliferation of retinoblastoma cells. Materials and Methods: The protein expression was analyzed in 30 retinoblastoma samples from paraffin block ...
Hendrian Dwikoloso Soebagjo +3 more
doaj
Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis. [PDF]
Cell Death DiscovSchmidt MF +10 more
europepmc +2 more sources