Results 111 to 120 of about 61,337 (245)
Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived fas ligand [PDF]
Activated microglia may be detrimental to neuronal survival in a number of neurodegenerative diseases. Thus, strategies that reduce microglial neurotoxicity may have therapeutic benefit.
Jones, F +3 more
core
This protocol describes an ELISAassay for measurement of FAS ligand (FASL, CD95L)insupernatants collected from T cell dependent cytotoxicity (TDCC) cultures after BiTE® treatment.
Sandra L. Ross +7 more
openaire +1 more source
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde +6 more
wiley +1 more source
Killer B Lymphocytes and their Fas Ligand Positive Exosomes as Inducers of Immune Tolerance
Induction of immune tolerance is a key process by which the immune system is educated to modulate reactions against benign stimuli such as self-antigens and commensal microbes.
Steven Karl Lundy +4 more
doaj +1 more source
Angular dependence of Josephson currents in unconventional superconducting junctions [PDF]
Josephson effect in junctions between unconventional superconductors is studied theoretically within the model describing the effects of interface roughness.
A. A. Golubov +7 more
core +5 more sources
A Crazy Idea: Ibn Sīnā on Hylomorphism, the Elements, Mixture and Evolutionary Processes
ABSTRACT Ibn Sīnā (c. 973‐1037), the Avicenna of Latin fame, developed a unique theory of the elements and their status in mixtures that severely challenged the views of earlier natural philosophers and in its turn was severely challenged by later Latin Schoolmen in the West.
Jon McGinnis
wiley +1 more source
The role of T cells in sepsis of distinct infectious aetiologies
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu +5 more
wiley +1 more source
Phyllanthus emblica Exerts Therapeutic Potential in Oral Cancer Through Multiple Pathways
Graphic Illustration of the Multifaceted Therapeutic Potential of PEWE, 1. Phyllanthus emblica water extract (PEWE) demonstrates potent anticancer effects against oral cancer by inhibiting cell proliferation, migration, and invasion while inducing apoptosis and autophagy. 2.
Tai‐Pei Lin +11 more
wiley +1 more source
The ground state energy of a massive scalar field in the background of a semi-transparent spherical shell [PDF]
We calculate the zero point energy of a massive scalar field in the background of an infinitely thin spherical shell given by a potential of the delta function type. We use zeta functional regularization and express the regularized ground state energy in
Abramowitz M +10 more
core +2 more sources
In OKT3‐treated human PBMCs, Wnt signaling was downregulated, and co‐treatment with the Wnt activator CHIR99021 reduced T cell activation and apoptosis. In humanized mice, transcriptomic profiling revealed upregulation of genes associated with T cell activation, cytokine and ROS production, and apoptosis, with downregulation of canonical Wnt signaling.
Myeongjin Choi +8 more
wiley +1 more source

