Results 31 to 40 of about 19,974 (255)

Piperine enhances contractile force in slow‐ and fast‐twitch muscle [PDF]

The Journal of Physiology
AbstractPiperine has been shown to bind to myosin and shift the distribution of conformational states of myosin molecules from the super‐relaxed state to the disordered relaxed state. However, little is known about the implications for muscle force production and potential underlying mechanisms.
Jon Herskind, Niels Ørtenblad, Arthur J. Cheng, Peter Pedersen, Kristian Overgaard   +4 more
openaire   +3 more sources

Physical inactivity induces insulin resistance in plantaris muscle through protein tyrosine phosphatase 1B activation in mice

Frontiers in Physiology, 2023
Inactivity causes insulin resistance in skeletal muscle and exacerbates various lifestyle-related diseases. We previously found that 24-h hindlimb cast immobilization (HCI) of the predominantly slow-twitch soleus muscle increased intramyocellular ...
Saori Kakehi, Saori Kakehi, Yoshifumi Tamura, Yoshifumi Tamura, Shin-ichi Ikeda, Shin-ichi Ikeda, Naoko Kaga, Hikari Taka, Yuya Nishida, Ryuzo Kawamori, Ryuzo Kawamori, Hirotaka Watada, Hirotaka Watada   +12 more
doaj   +1 more source

Comparative analysis of the transcriptomes of EDL, psoas, and soleus muscles from mice

BMC Genomics, 2020
Background Individual skeletal muscles have evolved to perform specific tasks based on their molecular composition. In general, muscle fibers are characterized as either fast-twitch or slow-twitch based on their myosin heavy chain isoform profiles.
Pabodha Hettige, Uzma Tahir, Kiisa C. Nishikawa, Matthew J. Gage   +3 more
doaj   +1 more source

Charge Movement in a Fast Twitch Skeletal Muscle from Rat

Biophysical Journal, 1983
Voltage-dependent charge movement in the rat omohyoid muscle was investigated using the three microelectrode voltage clamp technique. The charge that moved during a depolarization from the holding potential (-90 mV) to the test potential, V, increased with increasing V, saturating around 0 mV. The charge vs.
Simon, B.J., Beam, K.G.
openaire   +2 more sources

Prediction of muscle fiber composition using multiple repetition testing

Biology of Sport, 2020
Direct determination of muscle fiber composition is invasive and expensive, with indirect methods also requiring specialist resources and expertise. Performing resistance exercises at 80% 1RM is suggested as a means of indirectly estimating muscle fiber ...
Elliott C.R. Hall, Evgeny A Lysenko, Ekaterina A. Semenova, Oleg V. Borisov, Oleg N. Andryushchenko, Liliya B. Andryushchenko, Tatiana F Vepkhvadze, Egor M. Lednev, Piotr Zmijewski, Daniil V Popov, Edward V. Generozov, Ildus I Ahmetov   +11 more
doaj   +1 more source

Histochemical Differentiation of Fibers in the Rat Slow and Fast Twitch Muscles.

The Japanese Journal of Physiology, 1991
Wistar male rats were sacrificed at 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, and 21 days, and at 5 and 10 weeks of age. The histochemical differentiation of slow twitch soleus and fast twitch plantaris muscle fibers was examined from the enzyme activities of adenosine triphosphatase (slow- or fast-contracting), succinate dehydrogenase (high- or low-oxidative)
ISHIHARA, Akihiko, TAGUCHI, Sadayoshi
openaire   +3 more sources

Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy

Acta Neuropathologica Communications, 2022
Spinal and bulbar muscular atrophy (SBMA) is an X-linked, neuromuscular neurodegenerative disease for which there is no cure. The disease is characterized by a selective decrease in fast-muscle power (e.g., tongue pressure, grip strength) accompanied by ...
Elana Molotsky, Yuhong Liu, Andrew P. Lieberman, Diane E. Merry   +3 more
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Need for speed: Human fast-twitch mitochondria favor power over efficiency

Molecular Metabolism
Objective: Human skeletal muscle consists of a mixture of slow- and fast-twitch fibers with distinct capacities for contraction mechanics, fermentation, and oxidative phosphorylation.
Sebastian Edman, Mikael Flockhart, Filip J. Larsen, William Apró   +3 more
doaj   +1 more source

Motor units in a fast‐twitch muscle of normal and dystrophic mice.

The Journal of Physiology, 1983
Isometric contractions of motor units, isolated functionally by ventral root splitting were recorded from extensor digitorum longus muscles of normal and dystrophic mice of the strain C57BL/6J dy2J/dy2J. Motor unit tetanic tension was significantly lower and both time to peak tension and to half‐relaxation of the twitch were significantly prolonged in ...
D S, Bateson, D J, Parry
openaire   +3 more sources