Results 41 to 50 of about 19,974 (255)

Changes in transcriptional activity of chronically stimulated fast twitch muscle [PDF]

FEBS Letters, 1983
mRNAs extracted from rabbit soleus, normal and 28‐day, indirectly stimulated tibialis anterior muscles were translated in an in vitro system. Analysis for translation products by 2‐dimensional electrophoresis showed fast myosin light chains in tibialis anterior, and slow myosin light chains in soleus muscle. The stoichiometry of the in vitro translated
Heilig, Annegard, Pette, Dirk
openaire   +2 more sources

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

A Systematic Review of the Safety and Tolerability of Theta Burst Stimulation in Children and Adolescents

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Theta burst stimulation (TBS) is often used in clinical practice and research protocols for adults with neuropsychiatric disorders. There are substantial knowledge gaps related to the application of TBS in children and adolescents.
Rana Elmaghraby, Qi Sun, Can Ozger, Julia Shekunov, Magdalena Romanowicz, Paul E. Croarkin   +5 more
wiley   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Isometric contractions of motor units in a fast twitch muscle of the cat

The Journal of Physiology, 1973
1. Isosmetric contractions of cat flexor digitorum longus whole muscles and of functionally isolated motor units have been measured under conditions similar to those used by Buller & Lewis (1965a).2. Motor unit twitch time to peak was inversely related to axonal conduction velocity.
J, Bagust, S, Knott, D M, Lewis, J C, Luck, R A, Westerman   +4 more
openaire   +3 more sources

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

Comparative Study of the Chemical Composition Disparities Between Fast-twitch and Slow-twitch Muscles in Marine Teleost Fishes

Progress in Fishery Sciences
Skeletal muscle contraction, which generates movement by pulling on the internal skeleton, is a distinctive mode of movement in vertebrates. Renowned for its flexibility, diversity, and efficiency, this mode of movement is significant for the individual ...
Huan WANG, Shufang LIU
doaj   +1 more source

Benchmarking Data‐Driven Control of Octopus‐Inspired Soft Arms in Underwater Environment

Advanced Intelligent Systems, EarlyView.
Underwater soft robots present safe, compliant interaction, yet reproducible control remains scarce. This work presents an open benchmark for octopus‐inspired arms: a smooth, velocity‐diverse data‐collection scheme produces a compact dataset to train a vanilla policy.
Muhammad Sunny Nazeer, Yasmin Tauqeer Ansari, Emanuele Solfiti, Baljinder Singh Bal, Matteo Lo Preti, Barbara Mazzolai, Cecilia Laschi   +6 more
wiley   +1 more source