Results 91 to 100 of about 7,771,896 (303)

Input Fast-Forwarding for Better Deep Learning

open access: yes, 2017
This paper introduces a new architectural framework, known as input fast-forwarding, that can enhance the performance of deep networks. The main idea is to incorporate a parallel path that sends representations of input values forward to deeper network ...
A Ibrahim   +4 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Establishment and Evaluation of a Novel Method Based on Loop-Mediated Isothermal Amplification for the Rapid Diagnosis of Thalassemia Genes

open access: yesRisk Management and Healthcare Policy, 2020
Wei-hua Wang,1,* Min Lin,2,* Hai-liang Li,3 Jun-yun Huang,1 Jiang-tao Chen,4,5 Xian-song Fang,6 Dong-mei Huang,1 Xu-xiang Xi,1 Qing-fei Zhao,1 Fang-li Song,7 Shao Huang,7 Tian-yu Zhong1 1Department of Laboratory Medicine, First Affiliated Hospital of ...
Wang W   +11 more
doaj  

The optimal time of day for training during Ramadan: A review study [PDF]

open access: yesJournal of Fasting and Health, 2014
Literature concerning the effects of Ramadan fasting on sports performance presents conflicting results. In this context, some studies reported a significant impairment of sports performance during the month of Ramadan.
Hamdi Chtourou   +4 more
doaj  

Growth hormone secretion during space flight and evaluation of the physiological responses of animals held in the research animal holding facility [PDF]

open access: yes
The spaceflight of the Research Animal Holding Facility (RAHF) on the Space Laboratory 3 (SL 3) provided the opportunity to evaluate the suitability of the RAHF for housing and maintaining experimental animals during spaceflight, and to determine changes
Fast, Thomas N.   +3 more
core   +1 more source

Fast Kinetics, High-Frequency Oscillations, and Subprimary Firing Range in Adult Mouse Spinal Motoneurons [PDF]

open access: bronze, 2009
Marin Manuel   +5 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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