Results 101 to 110 of about 4,832,014 (309)
FAST: Fast and Accurate Synoptic Texts
Abstract Many classical texts are available in multiple versions that almost always differ from each other due to transcription error and editorial discretion. One of the central challenges in the study of such texts is the preparation of a ‘synoptic’ text: an aligned presentation of the various versions in which corresponding words or ...
Oran Brill, Moshe Koppel, Avi Shmidman
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Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Fast Association Tests for Genes with FAST
Gene-based tests of association can increase the power of a genome-wide association study by aggregating multiple independent effects across a gene or locus into a single stronger signal. Recent gene-based tests have distinct approaches to selecting which variants to aggregate within a locus, modeling the effects of linkage disequilibrium, representing
Chanda, Pritam +3 more
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Wang W, Lin M, Li H, et al. Risk Manag Healthc Policy. 2020;13:303– 311 On page 309, Sensitivity and Specificity of LAMP Assays in Clinical Assay heading, last sentence “These results showed that the sensitivity and ...
Wang W +11 more
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Image processing for feature detection and extraction [PDF]
The present paper aims to conduct an experiment that compares different methods of detecting objects in images. Programs were developed to evaluate the efficiency of SURF, BRISK, MSER, and ORB object detection methods.
Nicolae APOSTOLESCU +1 more
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The article is devoted to the food consumption practices of the Ukrainian-minded educated class during the late 19th – early 20th cc. It is based mainly on the memoirs and diaries.
Olga Kazakevych
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