Results 91 to 100 of about 3,162,530 (287)

Establishment and Evaluation of a Novel Method Based on Loop-Mediated Isothermal Amplification for the Rapid Diagnosis of Thalassemia Genes [Corrigendum]

open access: yesRisk Management and Healthcare Policy, 2021
Wang W, Lin M, Li H, et al. Risk Manag Healthc Policy.  2020;13:303– 311 On page 309, Sensitivity and Specificity of LAMP Assays in Clinical Assay heading, last sentence “These results showed that the sensitivity and ...
Wang W   +11 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The Impact of Narcolepsy on Fasting (A Jurisprudential Study)

open access: yesJournal of Umm Al-Qura University for Shari'ah Sciences and Islamic Studies
Narcolepsy is a rare chronic brain disorder that causes sudden sleepiness at inappropriate times. It is a rare, long-term neurological condition that causes a person to suddenly fall asleep at inappropriate times, and it has various symptoms including ...
Aziza Saeed Al-Qarni
doaj   +1 more source

Image processing for feature detection and extraction [PDF]

open access: yesINCAS Bulletin
The present paper aims to conduct an experiment that compares different methods of detecting objects in images. Programs were developed to evaluate the efficiency of SURF, BRISK, MSER, and ORB object detection methods.
Nicolae APOSTOLESCU   +1 more
doaj   +1 more source

Fast Association Tests for Genes with FAST

open access: yesPLoS ONE, 2013
Gene-based tests of association can increase the power of a genome-wide association study by aggregating multiple independent effects across a gene or locus into a single stronger signal. Recent gene-based tests have distinct approaches to selecting which variants to aggregate within a locus, modeling the effects of linkage disequilibrium, representing
Chanda, Pritam   +3 more
openaire   +6 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

BETWEEN CITY AND VILLAGE: FOOD CONSUMPTION PRACTICES IN THE EVERYDAY LIFE OF THE UKRAINIAN INTELLIGENTSIA (THE LATE 19th – EARLY 20th CC.)

open access: yesМісто: історія, культура, суспільство, 2019
The article is devoted to the food consumption practices of the Ukrainian-minded educated class during the late 19th – early 20th cc. It is based mainly on the memoirs and diaries.
Olga Kazakevych
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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