Results 61 to 70 of about 5,346,682 (363)

Children\u27s takeaway and fast-food intakes: associations with the neighbourhood food intakes : associations with the neighbourhood food environment

open access: yes, 2009
Objective: The present study aimed to examine associations between availability of outlets where takeaway or fast food could be purchased and consumption of takeaway or fast food among children.Design Cross-sectional: Parents completed a questionnaire ...
Adrianopoulos, Nick   +4 more
core   +1 more source

Fast food and obesity in China [PDF]

open access: yesJournal of the American College of Cardiology, 2003
As Dr. DeMaria stated in his recent Editor’s Page [(1)][1], the introduction of fast food in America undoubtedly contributed to the increase in obesity. He also suggested that “the introduction of fast food overseas has been accompanied by a similar increase in obesity in these countries ...
openaire   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Pattern Of Fast Food Consumption Among Medical Students And Its Association With Obesity

open access: yesJournal of Rawalpindi Medical College, 2019
Background: Fast food consumption has been linked to obesity as it contains high saturated fatty acids, sugar, salt, and calories. We conducted this study to determine the pattern of fast food consumption amongst medical students and to assess the ...
Sara Usman   +3 more
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

The influence of gender, media, and internet usage on adolescents' fast food perception and fluid intake

open access: yesJournal of Health, Population and Nutrition, 2023
Background Understanding the factors that influence adolescent’s perception of fast food and their fluid consumption is crucial for designing effective nutrition education programs tailored to this population.
Ahmad R. Al-Haifi   +5 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Young children’s food brand knowledge. Early development and associations with television viewing and parent’s diet [PDF]

open access: yes, 2014
Brand knowledge is a prerequisite of children’s requests and choices for branded foods. We explored the development of young children’s brand knowledge of foods highly advertised on television – both healthy and less healthy.
Arredondo   +48 more
core   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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