Results 51 to 60 of about 4,306,015 (302)
Drosophila as a Robust Model System for Assessing Autophagy: A Review
Toxics, 2023 Autophagy is the process through which a body breaks down and recycles its own cellular components, primarily inside lysosomes. It is a cellular response to starvation and stress, which plays decisive roles in various biological processes such as ...
Esref Demir, Sam Kacew
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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A novel adipose loss-of-function mutant in Drosophila
FlyTo identify genes required for brain growth, we took an RNAi knockdown reverse genetic approach in Drosophila. One potential candidate isolated from this effort is the anti-lipogenic gene adipose (adp).
Nicole A. Losurdo +3 more
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Humoral and Cellular Defense Mechanisms in Rebel Workers of Apis mellifera
Biology, 2021 The physiological state of an insect depends on efficiently functioning immune mechanisms such as cellular and humoral defenses. However, compounds participating in these mechanisms also regulate reproductive caste formation and are responsible for ...
Aneta Strachecka +6 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Ade2 Functions in the Drosophila Fat Body To Promote Sleep
G3: Genes, Genomes, Genetics, 2018 Metabolic state is a potent modulator of sleep and circadian behavior, and animals acutely modulate their sleep in accordance with internal energy stores and food availability.
Maria E. Yurgel +6 more
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Frontiers in Endocrinology, 2021 Many insect species have several genes coding for insulin-related peptides (IRPs), but so far only a single IRP gene has been identified in migratory locusts.
Jan A. Veenstra +3 more
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Sex Differences in Measures of Body Fat and Body Fat Distribution in the Elderly [PDF]
American Journal of Epidemiology, 1996 This study describes sex differences in obesity and body fat distribution using commonly used assessment methods in 140 men and 245 women age 65-96 years from Rancho Bernardo, California. Significant correlations were shown among all obesity measures. The waist/hip ratio was more strongly correlated with the truncal fat/leg fat ratio in women than in ...
D, Goodman-Gruen, E, Barrett-Connor
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Veterinary Medicine: Research and Reports, 2012 Gebin Li,1 Peter Lee,1 Nobuko Mori,1 Ichiro Yamamoto,1 Koh Kawasumi,1 Hisao Tanabe,2 Toshiro Arai11Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 2Komazawa Animal Hospital, Tokyo ...
Arai T +6 more
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