Results 61 to 70 of about 4,306,015 (302)

Serpentine and Vermiform Are Produced Autonomously to Fulfill Their Function in Drosophila Wings

Insects, 2023
Group I chitin deacetylases (CDAs), CDA1 and CDA2, play an essential role in cuticle formation and molting in the process of insect wing development. A recent report showed that trachea are able to take up a secreted CDA1 (serpentine, serp) produced in ...
Xubo Zhang, Yanan Ji, Bernard Moussian, Shumin Yang, Jianzhen Zhang, Tingting Zhang, Min Zhang   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Body condition of shorebirds upon arrival at their Siberian breeding grounds [PDF]

, 2009
Arctic breeding shorebirds carry substantial body stores on their long-distance migrations from their non-breeding grounds. Upon arrival at the breeding area the remains of these stores can be used for egg formation, insurance against poor feeding ...
Klaassen, Raymond, Tulp, Ingrid, Visser, G. Henk, Klaassen, Raymond H. G., Ens, Bruno J., Ens, B.J., Tulp, I., Schekkerman, H., Visser, G.H., Schekkerman, Hans, Tulp, I.Y.M., Klaassen, R.H.G.   +11 more
core   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

FAT-Richtlinie Dynamische Werkstoffkennwerte für die Crashsimulation

, 2022
Im Rahmen des AiF/FAT-Forschungsvorhabens 14205 ist die FAT-Richtline "Dynamische Werkstoffkennwerte für die Crashsimulation" (siehe [1]) zur zuverlässigen Bestimmung von crashrelevanten, dynamischen Werkstoffkennwerten für Crashsimulationen im ...
Blauel, J.G., Luke, M., Böhme, W., Rohr, I., Sun, D.-Z., Harwick, W.   +5 more
core   +1 more source

Effect of ivermectin on the life cycle and larval fat body of Culex quinquefasciatus

Brazilian Archives of Biology and Technology, 2004
The present work investigated the behavior, survival rate and lethal effect of 1.5 ppb ivermectin on Culex quinquefasciatus larvae, based on morphological and biological parameters, and possible alterations of their fat body.
Stenio Nunes Alves, José Eduardo Serrão, Giovani Mocelin, Alan Lane de Melo   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Differential Effects of Two Fermentable Carbohydrates on Central Appetite Regulation and Body Composition [PDF]

, 2012
Background: Obesity is rising at an alarming rate globally. Different fermentable carbohydrates have been shown to reduce obesity. The aim of the present study was to investigate if two different fermentable carbohydrates (inulin and β-glucan) exert ...
Ruey Leng Loo, Anastasovska, Jelena, Frost, G.S., Kieran M. Tuohy (139099), Arora Tulika, Bell Jimmy D., Raj Kumar Sharma (139101), Loo Ruey Leng, Tulika Arora, Swann, J. R., Sleeth Michelle, L., Gibson, Glenn R, Sleeth, M. J., Michele L Sleeth, Frost, G, Sharma, R. K., Bell, Jimmy D, Loo, RL, Bell, Jimmy D., Holmes, E, Anastasovska Jelena, Thomas, EL, Sleeth, Michele L, Swann, Jonathan R, Bell, J. D., Eddie R. Deaville (139109), Arora, T., Deaville, Eddie R, Frost, G., Kieran M Tuohy, Sleeth, M. L., Deaville, Eddie R., Jimmy D. Bell (111613), Thomas E. Louise, Bell, JD, Anastasovska, J., Sleeth Michele L., Thomas, E Louise, Thomas, E. L., Gibson, G.R., Frost, Gary, Leng Loo, R., Gary Frost, Holmes, E., E Louise Thomas, Michele L. Sleeth (139110), Eddie R Deaville, Holmes Elaine, Holmes, Elaine, Ruey Leng Loo (139090), Loo, R. L., Swann, Jonathan R., Glenn R Gibson, Deaville, ER, Thomas, E.L., Tuohy, Kieran M, Jelena Anastasovska, E. Louise Thomas (139111), Loo, Ruey Leng, Sleeth, Michele L., Glenn R. Gibson (139097), Tuohy, KM, Deaville, E. R., Arora, Tulika, Swann Jonathan R., Gibson, G. R., Sleeth, ML, Kumar Sharma, R., Gibson, Glenn R., Jonathan R Swann, Gary Frost (139113), Tuohy Kieran M., Sharma, RK, Sharma Raj Kumar, Jelena Anastasovska (139094), Frost Gary, Elaine Holmes (40919), Gibson, GR, Tuohy, K., Tulika Arora (139086), Deaville, E.R., Sharma, Raj Kumar, Gibson Glenn R., Thomas, E. Louise, Loo, R.L., Arora, T, Tuohy, Kieran Michael, Deaville Eddie R., Raj Kumar Sharma, Jonathan R. Swann (139105), Elaine Holmes, Anastasovska, J, Bell, J.D., Swann Jonathan, Jimmy D Bell, Swann, JR, Tuohy, Kieran M.   +96 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Three-compartment body composition changes in elite rugby league players during a super league season, measured by dual-energy X-ray absorptiometry. [PDF]

, 2011
This study investigated the acute changes in body composition that occur over the course of a competitive season in elite rugby league players. Twenty elite senior players from an English Super League rugby league team underwent a total-body dual-energy ...
O'Hara, J, Harley, JA, John P O'Hara, Jamie A Harley, Karen Hind, Hind, K   +5 more
core   +1 more source