Results 61 to 70 of about 6,022,993 (297)

The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial

open access: yesJournal of the International Society of Sports Nutrition, 2018
Background Betaine supplementation has been shown to improve body composition and some metrics of muscular performance in young men; but, whether betaine enhances body composition or performance in female subjects is currently unknown.
Jason Michael Cholewa   +7 more
doaj   +1 more source

High-Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts

open access: yesStem Cells International, 2022
Current research suggests that chronic high-fat dietary intake can lead to bone loss in adults; however, the mechanism by which high-fat diets affect the development of osteoporosis in individuals is unclear.
RunJiu Zhu   +8 more
doaj   +1 more source

The impact of weight loss on fat-free mass, muscle, bone and hematopoiesis health: Implications for emerging pharmacotherapies aiming at fat reduction and lean mass preservation.

open access: yesMetabolism: Clinical and Experimental
Incretin receptor agonists have revolutionized the treatment of obesity, achieving up to 15-25 % weight loss in many patients, i.e., at a rate approaching that achieved with bariatric surgery. However, over 25 % of total weight lost from both surgery and
Konstantinos Stefanakis   +2 more
semanticscholar   +1 more source

Impact of Genetic Variants on the Individual Potential for Body Fat Loss

open access: yesNutrients, 2018
The past decade has witnessed the discovery of obesity-related genetic variants and their functions through genome-wide association studies. Combinations of risk alleles can influence obesity phenotypes with different degrees of effectiveness across ...
Soyeon Cha   +7 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Potential benefits of blood flow restriction training in patients with type 2 diabetes: A narrative literature review

open access: yesBiomedical Human Kinetics
Study aim: This narrative review aims to critically discuss the potential beneficial effects of blood flow restriction (BFR) training on physiological outcomes, including muscle metabolism, insulin sensitivity, glucose metabolism, body composition, and ...
Trybulski Robert   +4 more
doaj   +1 more source

The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review

open access: yesNutrients, 2020
Exercise is an effective strategy for preventing and treating obesity and its related cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue browning, redistribution of energy substrates, optimization of global ...
Adrian M Gonzalez-Gil   +1 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Investigating weight loss resistance across the menopausal transition: a preliminary quantitative survey of resistance-trained women

open access: yesJournal of the International Society of Sports Nutrition
Background Many women enter midlife unaware of the physiological and hormonal changes associated with the menopause transition. This period is commonly characterized by increased fat mass and decreased lean body mass.
Anna Oelmann   +10 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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