Results 91 to 100 of about 4,193,745 (307)

Determinants of fat mass in prepubertal children [PDF]

British Journal of Nutrition, 2002
The aim of the present study was to compare variables of metabolism, physical activity and fitness to body composition in normal and overweight children in a cross-sectional study design. Body composition was assessed by anthropometric measurements and bioelectrical impedance analysis in forty-eight prepubertal children (age 5–11 years, thirteen normal-
M J, Müller, A, Grund, H, Krause, M, Siewers, A, Bosy-Westphal, H, Rieckert   +5 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Evaluation of Bioelectrical Impedance Analysis for Identifying Overweight Individuals at Increased Cardiometabolic Risk:A Cross-Sectional Study [PDF]

, 2014
OBJECTIVE: To investigate whether bioelectrical impedance analysis could be used to identify overweight individuals at increased cardiometabolic risk, defined as the presence of metabolic syndrome and/or diabetes.DESIGN AND METHODS: Cross-sectional study
Lamb Maxine J. E., Christopher D Byrne, Wilson, J.F., Lamb, M.J.E., Wild, S.H., Lamb, Maxine J E, Byrne, Christopher D, Wild, Sarah H; id_orcid, Wilson James F., Byrne Christopher D., Sarah H Wild, James F Wilson, Wild Sarah H., Wilson, James F; id_orcid, Byrne, Christopher D., Maxine J E Lamb   +15 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effect of fat mass and lean mass on bone mineral density in postmenopausal and perimenopausal Thai women

International Journal of Women's Health, 2013
Sirianong Namwongprom,1 Sattaya Rojanasthien,2 Ampica Mangklabruks,3 Supasil Soontrapa,4 Chanpen Wongboontan,5 Boonsong Ongphiphadhanakul61Clinical Epidemiology Program and Department of Radiology, 2Department of Orthopaedics, 3Department of Internal ...
Namwongprom S, Rojanasthien S, Mangklabruks A, Soontrapa S, Wongboontan C, Ongphiphadhanakul B   +5 more
doaj  

Extent of Emphysema on HRCT Affects Loss of Fat-free Mass and Fat Mass in COPD

Internal Medicine, 2009
Although muscle loss is thought to be a prognostic factor in chronic obstructive pulmonary disease (COPD), its determinants remain unclear.To verify the hypothesis that fat-free mass (FFM) and fat mass (FM) are associated with the extent of emphysema in COPD patients.A total of 112 stable, male current or ex-smokers with or without COPD attending a ...
Kurosaki, Hiroko, Ishii, Takeo, Motohashi, Norihisa, Motegi, Takashi, Yamada, Kouichi, Kudoh, Shoji, Jones, Rupert C.M., Kida, Kozui   +7 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Mass observation / by Mass Observation.

, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core  

The causes of individual and seasonal variation in the metabolic rate of knot calidris canutus [PDF]

, 1998
Basal metabolic rate (BMR), an individual bird's minimum rate of energy expenditure, was followed in adult and juvenile captive Knot throughout their annual cycle, in conjunction with measurements of total body mass (BM) and body composition (lean mass ...
Selman, Colin
core