Results 51 to 60 of about 77,511 (304)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
酶法制备人乳替代脂的研究进展Research progress on enzymatic preparation of human milk fat substitutes
Zhongguo youzhi人乳替代脂是一类模拟母乳脂组成的结构脂质，为促进人乳替代脂的绿色高效生产，介绍了母乳脂的甘油三酯组成，对人乳替代脂的酶法制备工艺以及实际应用的研究现状进行了分析、总结和探讨，并展望了未来的研究方向。我国母乳脂中1-油酸-2-棕榈酸-3-亚油酸甘油三酯(OPL)含量最高，其次为1,3-二油酸-2-棕榈酸甘油三酯(OPO)。人乳替代脂的酶法制备工艺包括酯-酯交换法、一步酸解法、醇解-酯化两步法、两步酸解法、酯交换-酸解两步法等。提高酶的催化活性与位置选择性、抑制酰基迁移等是未来酶法制备人乳替代脂的研究方向 ...
陈行飞1，2，张羽飞2,3，李雅丽2，郑明明1，2,3，王俊1 CHEN Hangfei1,2, ZHANG Yufei2,3, LI Yali2, ZHENG Mingming1,2,3, WANG Jun1
doaj +1 more source
Frontiers in Public Health, 2022 Proteins are essential components in human nutrition, and animal products are usually the primary sources of human ingestion. However, the number of adherents to vegetarian and vegan diets has grown significantly, highlighting the need for alternatives ...
Bernardo Romão +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Food intake of European adolescents in the light of different food-based dietary guidelines : results of the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) study [PDF]
, 2011 Objective: Since inadequate food consumption patterns during adolescence are not only linked with the occurrence of obesity in youth but also with the subsequent risk of developing diseases in adulthood, the establishment and maintenance of a healthy ...
Cuenca-Garcia, Magdalena +15 more
core +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source