Results 41 to 50 of about 3,609,848 (355)

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Bone creep-fatigue damage accumulation

Journal of Biomechanics, 1989
Creep and fatigue tests were performed on human femoral cortical bone and the results were compared to a cumulative damage model for bone fracture. Fatigue tests in tension, compression, and reversed loading with a tensile mean stress were conducted at 2 Hz and 0.02 Hz.
W E, Caler, D R, Carter
openaire   +2 more sources

Parametric probabilistic approach for cumulative fatigue damage using double linear damage rule considering limited data [PDF]

International Journal of Fatigue, 2019
This work proposes a parametric probabilistic approach to model damage accumulation using the double linear damage rule (DLDR) considering the existence of limited experimental fatigue data. A probabilistic version of DLDR is developed in which the joint
J. Dias, S. Ekwaro-Osire, Americo Cunha Jr, S. Dabetwar, Abraham Nispel, Fisseha M. Alemayehu, Haileyesus B. Endeshaw   +6 more
semanticscholar   +1 more source

Development of ANN Model for the Prediction of VIV Fatigue Damage of Top-tensioned Riser

MATEC Web of Conferences, 2018
Marine riser experiences vortex-induced vibration (VIV) caused by current, leading to fatigue damage if VIV is not considered in design of riser. Estimation of VIV fatigue damage is essential in designing feasible and operable riser.
Wong Eileen Wee Chin, Choi Han Suk, Kim Do Kyun, Hashim Fakhruldin Mohd   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Knee joint neuromuscular activation performance during muscle damage and superimposed fatigue [PDF]

, 2012
This study examined the concurrent effects of exercise-induced muscle damage and superimposed acute fatigue on the neuromuscular activation performance of the knee flexors of nine males (age: 26.7 ± 6.1yrs; height 1.81 ± 0.05m; body mass 81.2 ± 11.7kg ...
Behm D. G., Brockett C. L., Claire Minshull, David Rees, Enoka R. M., Foley J. M., Gleeson N. P., Hopkins J. T, Hortobagyi T., Morgan D. L., Nigel Gleeson, Roger Eston, Saxton J. M.   +12 more
core   +1 more source

Energy dissipation and damage evolution for dynamic fracture of marble subjected to freeze-thaw and multiple level compressive fatigue loading

International Journal of Fatigue, 2021
For rock engineering in cold regions, rock is often subjected to coupled fatigue conditions of freeze-thaw (F-T) and stress disturbance. Rock fracture evolution and energy mechanism under room temperature and constant stress amplitude loading condition ...
Y. Wang, S. Gao, Cong Li, Junjie Han
semanticscholar   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Novel direct method on the life prediction of component under high temperature-creep fatigue conditions [PDF]

, 2013
This paper presents a novel direct method, within the Linear Matching Method (LMM) framework, for the direct evaluation of steady state cyclic behaviour of structures subjected to high temperature – creep fatigue conditions.
Chen, Haofeng, Gorash, Yevgen
core