Results 111 to 120 of about 3,900,867 (308)

Functional analysis of leishmania cyclopropane fatty acid synthetase [PDF]

, 2012
The single gene encoding cyclopropane fatty acid synthetase (CFAS) is present in Leishmania infantum, L. mexicana and L. braziliensis but absent from L. major, a causative agent of cutaneous leishmaniasis. In L.
Mottram Jeremy C., Evans, K.J., Samuel O. Oyola (112546), Barbara A. Smith (112553), Smith, Barbara A., Terry K Smith, Smith Barbara A., Samuel O Oyola, Smith, Deborah F., Paul M Kaye, James D. Hilley (112558), Kaye, Paul M., Evans, Krystal J., Smith, Terry K., Smith, B.A., Oyola, Samuel O., Hilley, J.D., Mottram, J.C., Kaye, P.M., Oyola, S.O., Jeremy C. Mottram (112563), Smith Terry K., Terry K. Smith (112550), Smith, D.F., Mottram, Jeremy C., Hilley James D., Oyola Samuel O., Paul M. Kaye (54054), Deborah F. Smith (112029), Krystal J Evans, Evans Krystal J., Jeremy C Mottram, Kaye Paul M., James D Hilley, Smith, T.K., Barbara A Smith, Krystal J. Evans (112547), Smith Deborah F., Deborah F Smith, Hilley, James D.   +39 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Polyunsaturated fatty acids in various macroalgal species from north Atlantic and tropical seas [PDF]

, 2011
Background - In this study the efficacy of using marine macroalgae as a source for polyunsaturated fatty acids, which are associated with the prevention of inflammation, cardiovascular diseases and mental disorders, was investigated.
Keulen, H., van, Willem A Brandenburg, Ginneken, V.J.T., van, Brandenburg, W.A., Johannes PFG Helsper, Herman van Keulen, Visser, W., de, Vincent JT van Ginneken, Helsper, J.P.F.G., Willem de Visser   +9 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The characterization of adipose tissue in distinct anatomical regions of the Kazakh horse: a comprehensive analysis of the morphology, fatty acid profile, and lipidomic profile

Frontiers in Animal Science
The Kazakh horse is one of the important horse breeds in China. The distribution of its adipose tissue and the characteristics of lipid metabolism play a crucial role in the horse’s fat utilization efficiency, meat quality, and energy storage. This study
Ran Wang, Wanlu Ren, Wanlu Ren, Luling Li, Zexu Li, Shikun Ma, Dehaxi Shan, Qiuping Huang, Yi Su, Jianwen Wang, Jianwen Wang   +10 more
doaj   +1 more source

METABOLISM OF FATTY ACIDS IN CHOLESTEROLESTER

The Keio Journal of Medicine, 1970
Cholesterol-C14-oleate and cholesterol-C14-linoleate were administered in albino rats either orally through a catheter or by injection, to measure the specific activity of each fat in the serum, liver and depot fat in a chronological sequence.As a result, scarcely any radioactivity was demonstrated in triglyceride, diglyceride, monoglyceride, free ...
openaire   +3 more sources

Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics [PDF]

, 2013
There is a critical need for mapping early metabolic changes in schizophrenia to capture failures in regulation of biochemical pathways and networks.
Buckley, P, Kaddurah-Daouk, Rima, George G. Dougherty (436720), Peter Buckley (436718), Nasrallah Henry A., Joseph McEvoy, Baillie Rebecca A., Yao Jeffrey K., Nasrallah, HA, Zhu, H, Nasrallah, Henry A., Dougherty, GG, Zhu, Hongjie, Keshavan, Matcheri, Kaddurah-Daouk Rima, Peter Buckley, Keshavan, Matcheri S., Keshavan Matcheri S., Matcheri S Keshavan, Keshavan, MS, George G Dougherty, McEvoy, J, Hongjie Zhu (152174), Dougherty, George G., Henry A Nasrallah, Matcheri S. Keshavan (311472), Rima Kaddurah-Daouk (152187), Buckley Peter, Baillie, RA, McEvoy, Joseph, Hongjie Zhu, Rima Kaddurah-Daouk, McEvoy Joseph, Henry A. Nasrallah (436719), Yao, Jeffrey K., Joseph McEvoy (311475), Buckley, Peter, Kaddurah-Daouk, R, Rebecca A Baillie, Rebecca A. Baillie (152180), Dougherty George G., Jeffrey K Yao, Baillie, Rebecca A., Jeffrey K. Yao (311469), Yao, JK, Zhu Hongjie   +45 more
core   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Identifying biomarkers of hepatic fatty acid metabolism disorder in sevoflurane-induced brain developmental injury by bioinformatics analysis

Frontiers in Molecular Neuroscience
IntroductionExposure to sevoflurane in neonatal rats disrupts energy metabolism during brain development, which is associated with anesthetic-induced neurodevelopmental toxicity.
Haozheng Yuan, Yuying Lv, Pei Fan, Pengyu Jia, Kui Wang, Kailing Hu, Haodong Sun, Xinlin Chen, Pengbo Zhang   +8 more
doaj   +1 more source