The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye+16 more
wiley +1 more source
Fatty acid metabolism-derived prognostic model for lung adenocarcinoma: unraveling the link to survival and immune response. [PDF]
Wu RZ+8 more
europepmc +1 more source
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia+12 more
wiley +1 more source
Erratum: The inhibition of YTHDF3/m<sup>6</sup>A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer: Erratum. [PDF]
Zhong S+14 more
europepmc +1 more source
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
wiley +1 more source
The Splice Variant of the NCOR2 Gene BQ323636.1 Modulates ACSL4 Expression to Enhance Fatty Acid Metabolism and Support of Tumor Growth in Breast Cancer. [PDF]
Tsoi H+4 more
europepmc +1 more source
<i>S100a4</i><sup>+</sup> alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting the angiogenic function regulated by fatty acid metabolism. [PDF]
Huang H+11 more
europepmc +1 more source
Effects of maternal feeding of clofibrate on hepatic fatty acid metabolism in suckling piglet. [PDF]
Zhao J+7 more
europepmc +1 more source
Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature. [PDF]
Ma Z, Zheng M, Liu P.
europepmc +1 more source