Results 41 to 50 of about 1,126,784 (352)

Construction and validation of a fatty acid metabolism-related gene signature for predicting prognosis and therapeutic response in patients with prostate cancer [PDF]

PeerJ, 2023
Background Reprogramming of fatty acid metabolism is a newly-identified hallmark of malignancy. However, no studies have systematically investigated the fatty acid metabolism related-gene set in prostate cancer (PCa).
Hongjun Zhao, Tong Wu, Zehao Luo, Qinyao Huang, Sihua Zhu, Chunling Li, Zubing Zhang, Jiahao Zhang, Jianwen Zeng, Yuying Zhang   +9 more
doaj   +2 more sources

RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis

Cancer immunology research, 2020
The immune-suppressive effects of tumor-associated macrophages (TAM) are partially controlled by metabolic reprogramming. RIPK3 shifts TAMs to an antitumor phenotype in hepatocellular carcinoma by modulating fatty acid metabolism, thus decreasing ...
Lei Wu, X. Zhang, Lu Zheng, Huakan Zhao, Guifang Yan, Qi Zhang, Yu Zhou, Juan Lei, Jiangang Zhang, Jing-chun Wang, Rong Xin, Lu Jiang, Jin Peng, Qian Chen, S. Lam, G. Shui, Hongming Miao, Yongsheng Li   +17 more
semanticscholar   +1 more source

Lipid and fatty acid metabolism in trypanosomatids [PDF]

Microbial Cell, 2021
Trypanosomiases and leishmaniases are neglected tropical diseases that have been spreading to previously non-affected areas in recent years. Identification of new chemotherapeutics is needed as there are no vaccines and the currently available treatment options are highly toxic and often ineffective.
Marco Antonio Mendes Gomes, Roberto Kopke Salinas, Giovana Parreira de Aquino, Maria Fernanda Laranjeira-Silva   +3 more
openaire   +4 more sources

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria. [PDF]

PLoS ONE, 2012
BACKGROUND: Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA ...
Ulrike Mütze, Skadi Beblo, Linda Kortz, Claudia Matthies, Berthold Koletzko, Mathias Bruegel, Carmen Rohde, Joachim Thiery, Wieland Kiess, Uta Ceglarek   +9 more
doaj   +1 more source

Multi-omics analysis explores the effect of chronic exercise on liver metabolic reprogramming in mice

Frontiers in Cell and Developmental Biology, 2023
Background: The effect of exercise on human metabolism is obvious. However, the effect of chronic exercise on liver metabolism in mice is less well described.Methods: The healthy adult mice running for 6 weeks as exercise model and sedentary mice as ...
Zhaoxu Lu, Zhaoxu Lu, Zhaoxu Lu, Ping Qian, Ping Qian, Ping Qian, Jiahui Chang, Jiahui Chang, Jiahui Chang, Xuejia He, Xuejia He, Haifeng Zhang, Jian Wu, Ting Zhang, Ting Zhang, Jianxin Wu, Jianxin Wu, Jianxin Wu   +17 more
doaj   +1 more source

Intestinal metabolism of fatty acids [PDF]

Biochemical Journal, 1965
1. The effect of concentration on the oxidation and incorporation into lipids of lauric acid and linoleic acid by rings of rat small intestine has been studied in vitro. 2. In the absence of glucose, the oxidation of lauric acid in the range 0.01-5.0mm showed a maximum at 0.1mm. In the presence of glucose the maximum was at 0.5mm.
openaire   +3 more sources

Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism

Oncology Letters, 2020
Fatty acid metabolism is closely associated with the occurrence and development of tumors. The aim of the present study was to investigate whether the key enzyme involved in fatty acid synthesis, fatty acid synthase (FASN), mediates fatty acid changes ...
Shuo Xu, Tingting Chen, Li-Hua Dong, Tao Li, Hui Xue, Bo Gao, Xiaodong Ding, Hui Wang, Hua Li   +8 more
semanticscholar   +1 more source

Fatty Acid Metabolism, Bone Marrow Adipocytes, and AML

Frontiers in Oncology, 2020
Acute myeloid leukemia (AML) cells modulate their metabolic state continuously as a result of bone marrow (BM) microenvironment stimuli and/or nutrient availability. Adipocytes are prevalent in the BM stroma and increase in number with age.
Y. Tabe, M. Konopleva, M. Andreeff
semanticscholar   +1 more source

Fatty acid metabolism by the osteoblast [PDF]

Bone, 2018
The emergence of bone as an endocrine organ able to influence whole body metabolism, together with comorbid epidemics of obesity, diabetes, and osteoporosis, have prompted a renewed interest in the intermediary metabolism of the osteoblast. To date, most studies have focused on the utilization of glucose by this specialized cell, but the oxidation of ...
Ryan C. Riddle, Ryan C. Riddle, Priyanka Kushwaha, Michael J. Wolfgang   +3 more
openaire   +3 more sources

Fatty Acid Metabolism in Endothelial Cell

Genes, 2022
The endothelium is a monolayer of cells lining the inner of blood and lymphatic vessels. Endothelial cells (ECs) release subtracts that prevent platelet and leukocyte adhesion and aggregation and modulate blood flow, which is essential for the normal function of the vascular system. ECs play indispensable roles in angiogenesis, homeostasis, stimulus or
Bin Liu, Zhiyu Dai
openaire   +2 more sources