Results 41 to 50 of about 1,111,197 (376)
Frontiers in Cell and Developmental Biology, 2023 Background: The effect of exercise on human metabolism is obvious. However, the effect of chronic exercise on liver metabolism in mice is less well described.Methods: The healthy adult mice running for 6 weeks as exercise model and sedentary mice as ...
Zhaoxu Lu +17 more
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Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism
Cells, 2020 Myelin is critical for the proper function of the nervous system and one of the most complex cell–cell interactions of the body. Myelination allows for the rapid conduction of action potentials along axonal fibers and provides physical and trophic ...
Y. Poitelon +2 more
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Metabolomics of dietary fatty acid restriction in patients with phenylketonuria. [PDF]
PLoS ONE, 2012 BACKGROUND: Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA ...
Ulrike Mütze +9 more
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Construction and validation of a fatty acid metabolism-related gene signature for predicting prognosis and therapeutic response in patients with prostate cancer [PDF]
PeerJ, 2023 Background Reprogramming of fatty acid metabolism is a newly-identified hallmark of malignancy. However, no studies have systematically investigated the fatty acid metabolism related-gene set in prostate cancer (PCa).
Hongjun Zhao +9 more
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Meteoritic Abundances of Fatty Acids and Potential Reaction Pathways in Planetesimals [PDF]
Icarus, 2019, 319, 685-700, 2018 The origin of fatty acids on the prebiotic Earth is important as they likely formed the encapsulating membranes of the first protocells. Carbon-rich meteorites (i.e., carbonaceous chondrites) such as Murchison and Tagish Lake are well known to contain these molecules, and their delivery to the early planet by intense early meteorite bombardments ...
arxiv +1 more source
RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis
Cancer immunology research, 2020 The immune-suppressive effects of tumor-associated macrophages (TAM) are partially controlled by metabolic reprogramming. RIPK3 shifts TAMs to an antitumor phenotype in hepatocellular carcinoma by modulating fatty acid metabolism, thus decreasing ...
Lei Wu +17 more
semanticscholar +1 more source
Effect of physical inactivity on the oxidation of saturated and monounsaturated dietary Fatty acids: results of a randomized trial [PDF]
PLoS Clin Trials 1, 5 (2006) e27, 2007 OBJECTIVES: Changes in the way dietary fat is metabolized can be considered causative in obesity. The role of sedentary behavior in this defect has not been determined. We hypothesized that physical inactivity partitions dietary fats toward storage and that a resistance exercise training program mitigates storage.
arxiv +1 more source
Intestinal metabolism of fatty acids [PDF]
Biochemical Journal, 1965 1. The effect of concentration on the oxidation and incorporation into lipids of lauric acid and linoleic acid by rings of rat small intestine has been studied in vitro. 2. In the absence of glucose, the oxidation of lauric acid in the range 0.01-5.0mm showed a maximum at 0.1mm. In the presence of glucose the maximum was at 0.5mm.
openaire +3 more sources
Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism
Oncology Letters, 2020 Fatty acid metabolism is closely associated with the occurrence and development of tumors. The aim of the present study was to investigate whether the key enzyme involved in fatty acid synthesis, fatty acid synthase (FASN), mediates fatty acid changes ...
Shuo Xu +8 more
semanticscholar +1 more source
Fatty Acid Metabolism, Bone Marrow Adipocytes, and AML
Frontiers in Oncology, 2020 Acute myeloid leukemia (AML) cells modulate their metabolic state continuously as a result of bone marrow (BM) microenvironment stimuli and/or nutrient availability. Adipocytes are prevalent in the BM stroma and increase in number with age.
Y. Tabe, M. Konopleva, M. Andreeff
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