Results 61 to 70 of about 3,900,867 (308)

Determination of chlorinated fatty acids using SPE, XSD and GC/MS [PDF]

, 2004
Chlorinated fatty acids (ClFAs) account for a considerable portion of the extractable, organically bound chlorine (EOCl) in aquatic animals. Because of analytical difficulties little is as of yet known about their behaviour in organisms.
Åkesson-Nilsson, Gunilla
core   +1 more source

Fatty acid metabolism suppresses neonatal cardiomyocyte proliferation by increasing PDK4 and HMGCS2 expression through PPARδ.

PLoS ONE
Cardiomyocytes lose their capacity to regenerate immediately after birth. Simultaneously, cardiomyocytes change energy metabolism from glycolysis to oxidative phosphorylation, especially using fatty acids.
Shota Tanaka, Akane Hirota, Yoshiaki Okada, Masanori Obana, Yasushi Fujio   +4 more
doaj   +1 more source

Effect of dietary supplementation with conjugated linoleic acid on markers of calcium and bone metabolism in healthy adult men.

, 2005
INTRODUCTION: Conjugated linoleic acid (CLA) has been shown to positively influence calcium and bone metabolism in experimental animals and cells in culture, but there are limited human data available.
Mullen, A, Cashman, KD, Jewell, C, Roche, HM, Doyle, L, Nugent, AP   +5 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Metabolomics analysis of sodium butyrate's effects on lipid metabolism in lambs' rumen-blood-muscle axis

Journal of Agriculture and Food Research
This study employed metabolomics approaches to systematically elucidate the key pathways and regulatory mechanisms by which sodium butyrate modulated fatty acid metabolism in ruminants, thereby addressing the knowledge gap regarding its roles in fatty ...
Yue Zhang, Hongbo Qu, Min Zhang, Yueying Guo, Lin Su, Lihua Zhao, Lina Sun, Yin Jin   +7 more
doaj   +1 more source

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells

Frontiers in Pharmacology, 2018
Impairment of hepatic fatty acid metabolism can lead to liver steatosis and injury. Testing drugs for interference with hepatic fatty acid metabolism is therefore important.
David Grünig, David Grünig, Urs Duthaler, Urs Duthaler, Stephan Krähenbühl, Stephan Krähenbühl, Stephan Krähenbühl   +6 more
doaj   +1 more source

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

, 2012
Nutrition during development affects risk of future cardiovascular disease. Relatively little is known about whether the amount and type of fat in the maternal diet affect vascular function in the offspring.
Masoodi, Mojgan, Geraldine F Clough, Karen A Lillycrop, Samuel P Hoile, Karen A. Lillycrop, Irvine, Nicola A., Philip C. Calder, Graham C. Burdge, Kelsall, Christopher J., Christopher Torrens (114420), Geraldine F. Clough, Geraldine F. Clough (114433), Christopher J. Kelsall, Lillycrop, Karen A., Calder, Philip C., Mojgan Masoodi (152735), Mark A. Hanson (114427), Hoile, Samuel P., Burdge, Graham C., Christopher J. Kelsall (173702), Mark A Hanson, Christopher J Kelsall, Graham C Burdge, Nicola A. Irvine (173711), Torrens, Christopher, Samuel P. Hoile, Nicola A Irvine, Graham C. Burdge (173729), Philip C Calder, Mojgan Masoodi, Hanson, Mark A., Philip C. Calder (173723), Christopher Torrens, Nicola A. Irvine, Clough, Geraldine F., Mark A. Hanson, Samuel P. Hoile (173705), Karen A. Lillycrop (173718)   +37 more
core   +1 more source

Differences in fatty acid composition between cerebral brain lobes in juvenile pigs after fish oil feeding [PDF]

, 2008
Very long-chain n-3 PUFA from fish are suggested to play a role in the development of the brain. Fish oil feeding results in higher proportions of n-3 PUFA in the brains of newborn piglets. However, the effect of fish oil on the fatty acid composition of
Coronel, R., den Ruijter, Hester M., Brummer, Robert-Jan M., Den Ruijter, H.M., Kok, F.J., Ruijter, H.M., den, Brouwer, Ingeborg A., Brouwer, I.A.; id_orcid, Katan, Martijn B., Brummer, R.J., Kok, Frans J., Brummer, Robert,, Zock, Peter L., Brouwer, I.A., Beekman, J., Ruijter, H.M. den, Dullemeijer, C., Katan, M.B.; id_orcid, Zock, P.L., Beekman, Jet, Katan, M.B., Coronel, Ruben, Dullemeijer, Carla   +22 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Intergenerational metabolic toxicity of perfluorooctanesulfonic acid exposure in adult offspring rats: a multi-omics approach

Frontiers in Endocrinology
IntroductionPerfluorooctane sulfonate (PFOS), known as a critical endocrine disruptor, was linked to potential intergenerational effect in population studies.
Guoqi Yu, Guoqi Yu, Guoqi Yu, Tingyu Luo, Xiaona Huo, Xi Meng, Liping Feng, Yan Sun, Yongjie Liu, Jun Zhang, Jun Zhang, Jun Zhang   +11 more
doaj   +1 more source