Results 191 to 200 of about 543,048 (306)

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

The blood lipidome fatty acid profile predicts the disease risk and clinical phenotypes of Alzheimer’s disease: associations from two prospective cohort studies [PDF]

Alzheimers Dement
Xu W, Huang L, Tan C, Tan L.
europepmc   +2 more sources

Distinguishing avocado oil quality based on fatty acid profile using PCA: A review of influencing factors and research gaps. [PDF]

J Food Drug Anal
Fernando D, Madja ARA, Azizah N, Hastuti AAMB, Rohman A.   +4 more
europepmc   +1 more source

Asia chemical profile: fatty acids

Focus on Surfactants, 2018
openaire   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Herbal maceration modulates fatty acid profile of cold-pressed oils and preserves antioxidant activity during long-term storage. [PDF]

Sci Rep
Laskoś K, Waligórski P, Pisulewska E, Janowiak F, Sadura-Berg I, Czyczyło-Mysza IM.   +5 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Evaluation of Different Terrestrial Oils as an Alternative to Dietary Fish Oil on Feed Physical Properties, Growth, Feed Utilization, and Fatty Acid Profile of Gangetic Catfish (Mystus cavasius). [PDF]

Animals (Basel)
Helen ST, Dey T, Bharoteshwari A, Uddin KR, Kabir MA, Hasan MR, Hossain MS.   +6 more
europepmc   +1 more source

US chemical profile: fatty acids

Focus on Surfactants, 2016
openaire   +1 more source