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Essential fatty acids in mitochondria

Archives of Biochemistry and Biophysics, 1961
Abstract The fatty acid contents of mitochondria from chicken liver, beef heart, rat liver, catfish liver, carp liver, salmon liver, and salmon heart were determined by gas-liquid chromatography of the methyl esters. The degree of unsaturation of the fatty acids increased in the above order, and the molar amounts of essential fatty acids, arachidonic
T, RICHARDSON, A L, TAPPEL, E H, GRUGER
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ESSENTIAL FATTY ACIDS AND PROSTAGLANDINS

1974
Arachidonic acid takes part in a number of complicated enzymic processes in which not only the prostaglandins but also the intermediate products of their biosynthesis have important physiological effects. The prostaglandin-synthesizing system can convert a large number of nonnatural substrates, leading to the formation of substituted prostaglandins ...
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Essential Fatty Acids and Osteoarthritis

Arthritis Care & Research
ObjectiveInflammation worsens joint destruction in osteoarthritis (OA) and aggravates pain. Although n‐3 fatty acids reduce inflammation, different n‐3 fatty acids have different effects on inflammation and clinical outcomes, with eicosapentaenoic acid (EPA) having the strongest effect.
David T. Felson   +9 more
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Essential fatty acids and acne

Journal of the American Academy of Dermatology, 1986
Acne is characterized by hyperkeratosis of the follicular epithelium, leading to horny impactions that may lie dormant as open or closed comedones or may cause inflammation of the follicle. Although persons with acne have consistently been observed to have elevated levels of sebum secretion, no mechanism relating sebum secretion rates to comedogenesis ...
D T, Downing   +3 more
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Essential Fatty Acids Revisited

Archives of Pediatrics & Adolescent Medicine, 1980
Polyunsaturated fatty acids (PUFAs) are aliphatic monocarboxylic acids with two or more double bonds in any positional arrangement or geometric configuration. Those PUFAs that prevent or relieve the symptoms of dietary deficiency in humans and animals are named, therefore, the essential fatty acids (EFAs).
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Essential fatty acids and the skin

British Journal of Dermatology, 1989
The realisation that essential fatty acids are of crucial importance for the maintenance of a healthy skin coincided with their discovery. Burr and Burr (1) first described the symptoms of essential fatty acid deficiency thus: “An abnormal, scaly condition of the skin is observed between the 70th and 90th day of life.
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ECZEMA AND ESSENTIAL FATTY ACIDS

Archives of Pediatrics and Adolescent Medicine, 1947
DERMATOLOGIC conditions classified perforce under the comprehensive and admittedly unsatisfactory term "eczema" constitute one of the chief problems encountered in the practice of medicine. True enough, as diagnostic methods have improved, the number of clinical conditions so designated has become fewer.
A. E. HANSEN   +4 more
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Essential fatty acids and prostaglandins

Preventive Medicine, 1987
The World Health Organization's recommendation for dietary intake of essential fatty acids is 3% of energy (en%) of linoleate. Evidence from rat studies suggests that more than 3 en% is desirable for the regulation of eicosanoid metabolism. With such a low level of available linoleate, humans tend to synthesize more prostanoids than they do with 6% or ...
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Essential Fatty Acids - A Review

Current Pharmaceutical Biotechnology, 2006
Essential fatty acids (EFAs): cis-linoleic acid (LA) and alpha-linolenic acid (ALA) are essential for humans and their deficiency is rare in humans due to their easy availability in diet. EFAs are metabolized to their respective long-chain metabolites: dihomo-gamma-linolenic acid (DGLA), and arachidonic acid (AA) from LA; and eicosapentaenoic acid (EPA)
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Essential fatty acid requirements of cats: Pathology of essential fatty acid deficiency

American Journal of Veterinary Research, 1984
SUMMARY The pathologic changes of essential fatty acid (efa) deficiency were studied in specific-pathogen-free, domestic shorthair cats which were fed purified diets for 1.5 to 2.5 years. Cats fed an efa-deficient diet exhibited signs of deficiency: severe fatty degeneration of the liver, excessive fat in the kidneys, dystrophic mineralization of the ...
M L, MacDonald   +4 more
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