Results 201 to 210 of about 1,436,231 (357)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

In the Marathon toward Achieving Efficient Enzymatic Decarboxylation of Fatty Acids. [PDF]

ACS Cent Sci
Winkler CK, Kroutil W.
europepmc   +1 more source

Absorption of very-long-chain saturated fatty acids in totally hydrogenated fish oil [PDF]

, 2000
Linda Granlund, Laila N. Larsen, Erling N. Christiansen, Jan I. Pedersen   +3 more
openalex   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Multivariate fetal growth trajectory modeling and its association with maternal fatty acids. [PDF]

Sci Rep
Huang S, Tang JJ, Chi HB, Zhang HW, Fan XY, Tang F, Lin XS, Yang BR, Qi HB, Xia YY, Han TL, Zhang H.   +11 more
europepmc   +1 more source

Rapid colorimetric micromethod for free fatty acids

, 1967
Robert D. MacKenzie, Thomas R. Blohm, Edward M. Auxier, Andrew C. Luther   +3 more
openalex   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Progress on Omega-3 fatty acids for the comprehensive and targeted treatment of spinal cord injury. [PDF]

Bone Res
Yuan Z, Shi L, Tao XN, Fan X, Zheng H, Shang Y, Zhao X, Yang F, Lin H, Xiao P, Chu B, Qiu J, Zong S, Ran N, Kong X, Sun JP, Zhou H, Feng S.   +17 more
europepmc   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

The ratio of omega-6 fatty acids to omega-3 fatty acids mediating the effect of gastroesophageal reflux disease on pancreatic cancer risk: a two-step mediation Mendelian randomisation study. [PDF]

BMC Gastroenterol
Ouyang J, Zhang R, Lv W, Lu Y.
europepmc   +1 more source