Results 221 to 230 of about 1,463,233 (357)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Process optimization and characterization of fatty acids and lipid concomitants in the aqueous extraction of camellia oil. [PDF]

RSC Adv
Fan H, Qin L, Zhong H, Chen Y, Wang Q, Zha W, Chen S, Zhu Y.   +7 more
europepmc   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Omega-3 fatty acids improve lipid metabolism by regulating miR-34a. [PDF]

Sci Rep
Li L, Tang Y, Wang X, Wang C, Song G.
europepmc   +1 more source

Using genomes sequences to identify causal variants for milk fatty acids in dairy cattle

, 2015
Armelle Govignon-Gion, Marie-Pierre Sanchez, Pascal Croiseau, Anne Barbat, Sébastien Fritz, Mekki Boussaha, Mickaël Brochard, Didier Boichard   +7 more
openalex   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Recent advances in microbial production of odd-chain fatty acids. [PDF]

World J Microbiol Biotechnol
Timmers RA, de Vicente M, Rosa-Masegosa A, Romero E, Tomás-Pejó E, González-Fernández C.   +5 more
europepmc   +1 more source

Impact of dietary propionate on fructose-induced changes in lipid metabolism, gut microbiota and short-chain fatty acids in mice

, 2020
Christine Brütting, Milena Lara Bisch, Corinna Brandsch, Frank Hirche, Gabriele I. Stangl   +4 more
openalex   +2 more sources

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source

Machine learning and experiment reveals gut microbial predictors of functional fatty acids in pork. [PDF]

Food Chem X
Pan L, Li Z, Zhu Q, Wang C, Ouyang Q, Huang X, Zhou C, Hung I, Liu C, Xu K, Yin J, Li Y, Yin Y.   +12 more
europepmc   +1 more source