Results 51 to 60 of about 1,254,981 (306)

Role of blood plasma fatty acids in pathogenesis of stable anginapectoris

Бюллетень сибирской медицины, 2007
In men and women suffering from stable angina pectoris of 1-2 functional classes and aged from 35 to 69 years old, decrease of C 23:0 and increase of C 18:1(11) fatty acids was observed regardless of sex, the content of the rest fatty acids changed ...
V. V. Novitsky, R. S. Karpov, S. V. Klimenkov, A. B. Salmina, M. Yu. Kotlovsky, S. V. Mashkovskaya, D. A. Kirichenko, R. A. Butyanov, A. P. Kouskaev, Ye. V. Bolshakova, Yu. V. Kotlovsky   +10 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Treatment of type 2 diabetes by free fatty acid receptor agonists [PDF]

, 2014
Dietary free fatty acids (FFAs), such as ω-3 fatty acids, regulate metabolic and anti-inflammatory processes, with many of these effects attributed to FFAs interacting with a family of G protein-coupled receptors.
Hudson, Brian D., Milligan, Graeme, Ulven, Trond, Watterson, Kenneth R.   +3 more
core   +2 more sources

An in vitro model for essential fatty acid deficiency: HepG2 cells permanently maintained in lipid-free medium.

Journal of Lipid Research, 1992
A stable essential fatty acid-deficient cell type, known as HepG2-EFD, was derived from the lipoprotein-producing human hepatoma cell line HepG2. These cells are particularly useful for quantitative studies involving essential fatty acids (n-6 and n-3 ...
EE Furth, H Sprecher, EA Fisher, HD Fleishman, M Laposata   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The effect of dietary calcium and other nutritionally relevant divalent cations on fatty acid-soap formation : a dissertation presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Nutritional Sciences at Massey University, Manawatū, New Zealand [PDF]

, 2016
A growing amount of scientific evidence appears to support a relationship between dietary calcium (Ca) and body weight where increased dietary Ca intake leads to weight reduction and the faecal excretion of several fatty acids.
Stroebinger, Natascha
core  

Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]

, 2007
Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Andersson A, André Michael Toschke, António Guerra, Baylin A, Baylin A, Berenson GS, Berthold Koletzko, Decsi T, Demmelmair H, Di Stasi D, Folch J, Frank GC, Hamill PV, Hans Demmelmair, Katan MB, Koletzko B, Koletzko B, Kwiterovich, Lee J, Lenfant C, Livingstone MB, Luukkainen P, Ma J, Miettinen TA, Moilanen T, Moilanen T, National Cholesterol Education Program, Ntambi JM, Riboli E, Rockett HR, Schaeffer L, Sellmayer A, Serdula MK, Svensson BG, Vobecky JS, Zeleniuch-Jacquotte A   +35 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Effects of induced subacute ruminal acidosis on milk fat content and milk fatty acid profile [PDF]

, 2008
Two lactating dairy cows fitted with a rumen cannula received successively diets containing 0%, 20%, 34% and again 0% of wheat on a dry matter basis. After 5, 10 and 11 days, ruminal pH was measured between 8:00 and 16:00 hours, and milk was analysed for
Enjalbert, Francis, Nicot, Marie-Claude, Troegeler-Meynadier, Annabelle, Videau, Yannick   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source