Results 81 to 90 of about 1,436,231 (357)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Animal, 2008 Heating oils and fats may lead to cyclization of polyunsaturated fatty acids, especially those showing multiple double bonds like linolenic acid. Cyclohexenyl and cyclopentenyl fatty acids are subsequently present in some edible oils and these were ...
L. Bretillon +3 more
doaj +1 more source
Milk urea nitrogen and milk fatty acid compositions in dairy cows with subacute ruminal acidosis
Veterinární Medicína, 2020 The present study was aimed at comparing the milk urea nitrogen (MUN) and milk fatty acid (MFA) compositions in Holstein cows with subacute ruminal acidosis (SARA) to those values of Holstein cows that did not have SARA.
Kanber Kara
doaj +1 more source
The cytotoxicity of fatty acid/α-lactalbumin complexes depends on the amount and type of fatty acid [PDF]
, 2013 peer-reviewedComplexes of the milk protein, α-lactalbumin, and the fatty acid, oleic acid, have previously been shown to be cytotoxic. Complexes of α-lactalbumin and five different fatty acids (vaccenic, linoleic, palmitoleic, stearic, and elaidic acid ...
Aits +35 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
, 2021 Milk fat is one of the most complex lipid matrices, with more than 400 different fatty acids (FA) in its composition and most of them at trace levels. In the past decades, important achievements have been achieved in regard to dairy fat FA analysis due to the remarkable development of modern analytical techniques.
Gómez-Cortés, Pilar +2 more
openaire +2 more sources
Chemical analysis and biological activities of fatty acids from the liver of x-ray irradiated rabbit, the antitumor agent so-called OX [PDF]
, 1965 Chemical and biological characteristics of the unsaturated fatty acids from the liver of irradiated and non-irradiated animals and some unsaturated fatty acids in sale have been described.
Seno, Satimaru, Yamamoto, Michio
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Total Postprandial Hepatic Nonesterified and Dietary Fatty Acid Uptake Is Increased and Insufficiently Curbed by Adipose Tissue Fatty Acid Trapping in Prediabetes With Overweight [PDF]
, 2022 Run Zhou Ye +9 more
openalex +1 more source
A Simple Polarization for Powerful Preliminary Test of Oil Quality Level [PDF]
, 2015 In this paper, light polarization has been used to indicate level quality of various vegetable oils. A new indication of level quality used here was change of light polarization, and was measured using a simple pair of polarizer-analyzer.
Firdausi, K. Sofjan +3 more
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