Results 51 to 60 of about 96,897 (263)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bayesian Network Based Fault Tolerance in Distributed Sensor Networks

open access: yesJournal of Telecommunications and Information Technology, 2014
A Distributed Sensor Network (DSN) consists of a set of sensors that are interconnected by a communication network. DSN is capable of acquiring and processing signals, communicating, and performing simple computational tasks. Such sensors can detect and
B. Bhajantri Lokesh, N. Nalini
doaj   +1 more source

Programming Language Constructs Supporting Fault Tolerance [PDF]

open access: yesLeibniz Transactions on Embedded Systems, 2016
In order to render software viable for highly safety-critical applications, we describe how to incorporate fault tolerance mechanisms into the real-time programming language PEARL.
Houben, Christina, Houben, Sebastian
doaj   +1 more source

Fault-tolerance techniques for hybrid CMOS/nanoarchitecture [PDF]

open access: yes, 2010
The authors propose two fault-tolerance techniques for hybrid CMOS/nanoarchitecture implementing logic functions as look-up tables. The authors compare the efficiency of the proposed techniques with recently reported methods that use single coding ...
A. Melouki   +24 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Measuring the BDARX architecture by agent oriented system a case study [PDF]

open access: yes, 2018
Distributed systems are progressively designed as multi-agent systems that are helpful in designing high strength complex industrial software. Recently, distributed systems cooperative applications are openly access, dynamic and large scales.
Abdul Hamid, Noorhamreeza   +6 more
core  

Fault tolerance for holonomic quantum computation

open access: yes, 2013
We review an approach to fault-tolerant holonomic quantum computation on stabilizer codes. We explain its workings as based on adiabatic dragging of the subsystem containing the logical information around suitable loops along which the information ...
Brun, Todd A.   +2 more
core   +1 more source

Topological fault-tolerance in cluster state quantum computation [PDF]

open access: yes, 2007
We describe a fault-tolerant version of the one-way quantum computer using a cluster state in three spatial dimensions. Topologically protected quantum gates are realized by choosing appropriate boundary conditions on the cluster.
Abramsky S Coecke B   +21 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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