Results 231 to 240 of about 131,226 (308)

A Soft Robotic Fish With a Dielectric Elastomer Actuator Body and Negative Stiffness Spine

open access: yesAdvanced Robotics Research, EarlyView.
This work introduces a bio‐mimetic soft robotic fish driven by fiber‐reinforced dielectric elastomer actuators integrated as its body. By prestretching this active skin against a flexible spine, a negative stiffness system is created, enabling large‐amplitude bending.
Markus Koenigsdorff   +4 more
wiley   +1 more source

Multiphoton‐Printed Microrobotic Arrays Powered by Discrete, Monolithically Integrated Hydrogel Actuators

open access: yesAdvanced Robotics Research, EarlyView.
Functional surfaces are investigated as a foundation for reconfigurable microscale systems with sensing and actuation capabilities. Advances in additive manufacturing enable our development of planar arrays of hybrid‐material, compliant microdevices that convert environmental stimuli into programmed motion and visual responses.
Sandra Edward   +5 more
wiley   +1 more source

Systematic Exploration of 3D Concrete Printing Parameters for Conformal Printing on Sloped Surfaces

open access: yesAdvanced Robotics Research, EarlyView.
A conformal slicing algorithm is developed for robotic 3D concrete printing (3DCP) on sloped surfaces as a first step toward printing slab‐on‐grade foundations on uneven terrain. Systematic experiments quantify the effects of nozzle speed, extrusion rate, and toolpath direction on filament dimension and stability.
Paniz Farrokhsiar   +2 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

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