Results 81 to 90 of about 43,176 (313)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Geomorphic response to neotectonic activity in the Jura Mountains and in the southern Upper Rhine Graben [PDF]

, 2008
Present-day tectonic activity at the southern end of the Upper Rhine Graben in central Western Europe is evidenced by significant seismicity, which has been documented over hundreds of years.
Fraefel, Marielle
core   +1 more source

Geomechanics modeling of ultra-deep fault-controlled carbonate reservoirs and its application in development

Shiyou shiyan dizhi
To enhance the development efficiency of ultra-deep fault-controlled carbonate reservoirs, large-scale rock mechanical experiments were conducted to reveal the deformation and connectivity mechanisms of high-angle to near-vertical fault surfaces.
Zhenzhong CAI, Hui ZHANG, Ke XU, Guoqing YIN, Zhimin WANG, Haiying WANG, Ziwei QIAN, Yu ZHANG   +7 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Achieving Representative Faultloads in Software Fault Injection

, 2011
Given the complexity of modern software systems and its pervasiveness in many aspects of our lives, software faults (i.e., bugs) are a dangerous threat.
Natella, Roberto
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Fault detection for binary sensors in smart home environments

, 2015
Experiments in assisted living confirm that such systems can provide context-aware services that enable occupants to remain active and independent. They also demonstrate that abnormal sensor events hamper the correct identification of critical (and ...
Ye, Juan, Stevenson, Graeme, Graeme Stevenson, Simon Dobson, Juan Ye, Dobson, Simon   +5 more
core   +1 more source

SETTOFF : a fault tolerant flip-flop for building cost-efficient reliable systems [PDF]

, 2012
Conventional fault tolerance techniques either require big overheads or have limited reliability. We propose a novel fault tolerant flip-flop (SETTOFF) that addresses timing errors and soft errors in one cost-efficient architecture. In SETTOFF, most SEUs
Zwolinski, Mark, Yang Lin, Lin, Yang, Mark Zwolinski   +3 more
core   +1 more source

Response of the stream geomorphic index to fault activity in the Qujiang fault on the southeastern margin of the Qinghai-Xizang Plateau

地震科学进展
Based on 12.5 m resolution ALOS_PALSAR DEM data and hydrology analysis tool in Arcgis10.6, the stream geomorphic indices such as slope, relief degree of the land surface (RDLS), hypsometric integral (HI) and stream length gradient (SL) along the Qujiang ...
Xin Tan, Kuan Liang, Baoqi Ma
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source