Results 61 to 70 of about 788,688 (243)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Locating Sensors in Complex Engineering Systems for Fault Isolation Using Population-Based Incremental Learning

Energies, 2020
Fault diagnostics aims to locate the origin of an abnormity if it presents and therefore maximize the system performance during its full life-cycle.
Jinxin Wang, Zhongwei Wang, Xiuzhen Ma, Guojin Feng, Chi Zhang   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Classifying the Percentage of Broken Magnets in Permanent Magnet Synchronous Motors Using Combined Short-Time Fourier Transform and a Pre-Trained Convolutional Neural Network

Energies
In critical applications of electrical machines, ensuring validity and safety is paramount to prevent system failures with potentially hazardous consequences. The integration of machine learning (ML) technologies plays a crucial role in monitoring system
Amin Ghafouri Matanagh, Salih Baris Ozturk, Taner Goktas, Omar Hegazy   +3 more
doaj   +1 more source

ANALYSIS OF FAULTS AND DIAGNOSTICS TURNOUTS

Science and Transport Progress, 2007
The paper provides analysis of electric and mechanical defects of railway switching points. It has been establsished that mechanical defects cause failure of each sixth switching point at a station and each second at a marshalling hump during a year. Ways and means of remote continuous diagnostics of switching points have been offered. 
Parfenov, V. I., Razghonov, O. P., Kovryhin, M. O.   +2 more
openaire   +2 more sources

A framework and methods for on-board network level fault diagnostics in automobiles [PDF]

A significant number of electronic control units (ECUs) are nowadays networked in automotive vehicles to help achieve advanced vehicle control and eliminate bulky electrical wiring.
Suwatthikul, Jittiwut
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

A Digital Twin Framework for Monitoring and Fault Identification of Marine Internal Combustion Engines

Applied System Innovation
Monitoring the current technical condition of a marine internal combustion engine and diagnosing the causes of deviations of its operating parameters from reference values are important tasks for ensuring the efficient and safe operation of marine power ...
Dmytro Minchev, Roman Varbanets, Yurii Kucherenko, Pavlo Bratchenko   +3 more
doaj   +1 more source