Results 81 to 90 of about 8,566 (306)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Desk-top tutorial Demonstration of Model-based Fault Detection and Diagnosis [PDF]

, 2007
In this paper, a demonstration on the model-based approach for fault detection has been presented. The aim of this demo is to provide students a desk-top tool to start learning model-based approach.
Gu, Fengshou, Ball, Andrew, Elshanti, Ali, Shi, John Z.   +3 more
core  

Classifying the Percentage of Broken Magnets in Permanent Magnet Synchronous Motors Using Combined Short-Time Fourier Transform and a Pre-Trained Convolutional Neural Network

Energies
In critical applications of electrical machines, ensuring validity and safety is paramount to prevent system failures with potentially hazardous consequences. The integration of machine learning (ML) technologies plays a crucial role in monitoring system
Amin Ghafouri Matanagh, Salih Baris Ozturk, Taner Goktas, Omar Hegazy   +3 more
doaj   +1 more source

The comparison of fault distinguishability approaches – case study [PDF]

Bulletin of the Polish Academy of Sciences: Technical Sciences, 2019
A comprehensive characterization of four selected fault distinguishability methods is presented herein. All considered methods are derived from structural residual approaches referring to model-based diagnostics. In particular, these methods are based on
J.M. Kościelny, M. Bartyś, K. Rostek
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Non-Intrusive Fault Detection in Reciprocating Compressors [PDF]

, 2012
This research presents techniques developed for non-intrusive sensing and fault detection in reciprocating compressors driven by induction motors. These procedures are “non-intrusive” because they rely only on voltage and current signals measured on the ...
Leeb, Steven, Schantz, Christopher James
core   +1 more source

A simple state-based prognostic model for railway turnout systems [PDF]

, 2010
The importance of railway transportation has been increasing in the world. Considering the current and future estimates of high cargo and passenger transportation volume in railways, prevention or reduction of delays due to any failure is becoming ever ...
Baskan, Saim, Sevkli, Mehmet, Guclu, Adem, Camci, Fatih, Yilboga, Halis, Eker, Ömer Faruk   +5 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

An online-integrated condition monitoring and prognostics framework for rotating equipment [PDF]

, 2014
Detecting abnormal operating conditions, which will lead to faults developing later, has important economic implications for industries trying to meet their performance and production goals.
Alrabady, Linda Antoun Yousef
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source